MBNL2 抗体 (Middle Region)
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北京 101111
Quick Overview for MBNL2 抗体 (Middle Region) (ABIN2784554)
抗原
See all MBNL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- MBNL2 Antibody - middle region
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序列
- ENGRVIACFD SLKGRCSREN CKYLHPPTHL KTQLEINGRN NLIQQKTAAA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against MBNL2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MBNL2
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anti-Muscleblind-Like 2 (MBNL2) (AA 261-290), (C-Term) antibody
MBNL2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB32800 unconjugated
anti-Muscleblind-Like 2 (MBNL2) antibodyMBNL2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-Like 2 (MBNL2) (AA 260-290), (C-Term) antibodyMBNL2 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-Like 2 (MBNL2) (AA 46-95) antibodyMBNL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, Bat, 小鸡, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-Like 2 (MBNL2) (Middle Region) antibodyMBNL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51632-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MBNL2 (Muscleblind-Like 2 (MBNL2))
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别名
- MBNL2
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背景
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Background Information: MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
Gene Name: Muscleblind-like splicing regulator 2
Alternative Symbols: MBLL, MBLL39, PRO2032
Protein Name: Muscleblind-like 2 (Drosophila), isoform CRA_b EMBL EAX08969.1
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分子量
- 28kDa
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基因ID
- 10150
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NCBI登录号
- NP_005748
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UniProt
- O95205
抗原
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