(1 reference)-
- 抗原 See all FXYD5 抗体
- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FXYD5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SERPSPSTDV QTDPQTLKPS GFHEDDPFFY DEHTLRKRGL LVAAVLFITG
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against FXYD5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FXYD5
- Top Product
- Discover our top product FXYD5 Primary Antibody
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anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (N-Term) antibody
FXYD5 适用: 人, 小鼠, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 22-145) antibodyFXYD5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (C-Term) antibodyVerified FXYD5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 66-115) antibodyFXYD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 54-103) antibodyFXYD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 108-157) antibodyFXYD5 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 71-100) antibodyFXYD5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) (AA 70-100), (Middle Region) antibodyFXYD5 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 178 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "FXYD5 modulates Na+ absorption and is increased in cystic fibrosis airway epithelia." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 4, pp. L654-64, (2008) (PubMed).
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: "FXYD5 modulates Na+ absorption and is increased in cystic fibrosis airway epithelia." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 4, pp. L654-64, (2008) (PubMed).
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- 抗原
- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
- 别名
- FXYD5 (FXYD5 产品)
- 别名
- FXYD5 antibody, DYSAD antibody, IWU1 antibody, KCT1 antibody, OIT2 antibody, PRO6241 antibody, RIC antibody, EF-8 antibody, Oit2 antibody, FXYD domain containing ion transport regulator 5 antibody, FXYD domain-containing ion transport regulator 5 antibody, FXYD5 antibody, Fxyd5 antibody
- 背景
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FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein. This reference sequence was derived from AF161462.1 and ESTs, validated by multiple replicate ESTs and human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein. Two transcript variants have been found for this gene, and they are both predicted to encode the same protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu.].
Alias Symbols: HSPC113, IWU-1, IWU1, KCT1, OIT2, PRO6241, RIC, dysad, DYSAD
Protein Interaction Partner: UBC,
Protein Size: 178 - 分子量
- 19 kDa
- 基因ID
- 53827
- NCBI登录号
- NM_014164, NP_054883
- UniProt
- Q96DB9
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