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KCNQ4 抗体 (Middle Region)

KCNQ4 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501372
发货至: 中国
  • 抗原 See all KCNQ4 抗体
    KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
    抗原表位
    • 12
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 40
    • 13
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, Pig
    宿主
    • 24
    • 17
    • 1
    克隆类型
    • 25
    • 17
    多克隆
    标记
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNQ4 antibody is un-conjugated
    应用范围
    • 30
    • 19
    • 17
    • 15
    • 14
    • 13
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    SSRMGIKDRI RMGSSQRRTG PSKQHLAPPT MPTSPSSEQV GEATSPTKVQ
    预测反应
    Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against KCNQ4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human KCNQ4
    Top Product
    Discover our top product KCNQ4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 695 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
    别名
    KCNQ4 (KCNQ4 产品)
    别名
    KCNQ4 antibody, k(v)7.4 antibody, kv7.4 antibody, DFNA2 antibody, DFNA2A antibody, KV7.4 antibody, potassium voltage-gated channel subfamily Q member 4 antibody, potassium channel, voltage gated KQT-like subfamily Q, member 4 antibody, potassium voltage-gated channel, subfamily Q, member 4 antibody, KCNQ4 antibody, kcnq4 antibody, Kcnq4 antibody
    背景
    The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: DFNA2, KV7.4, DFNA2A
    Protein Interaction Partner: STIP1, STUB1, HSP90B1, HSP90AA1, HSPA8, DNAJA1, KCNQ3,
    Protein Size: 695
    分子量
    77 kDa
    基因ID
    9132
    NCBI登录号
    NM_004700, NP_004691
    UniProt
    P56696
    途径
    Sensory Perception of Sound
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