RCHY1 抗体 (N-Term)
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- 抗原 See all RCHY1 抗体
- RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 马, 兔, 绵羊, 犬, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RCHY1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KLYTCRLCHD NNEDHQLDRF KVKEVQCINC EKIQHAQQTC EECSTLFGEY
- 预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RCHY1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RCHY1
- Top Product
- Discover our top product RCHY1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 200 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))
- 别名
- RCHY1 (RCHY1 产品)
- 别名
- ARNIP antibody, CHIMP antibody, PIRH2 antibody, PRO1996 antibody, RNF199 antibody, ZNF363 antibody, Pirh2 antibody, Zfp363 antibody, Znf363 antibody, wu:fb37e07 antibody, zgc:101128 antibody, RCHY1 antibody, arnip antibody, chimp antibody, pirh2 antibody, harnip antibody, rnf199 antibody, znf363 antibody, pro1996 antibody, ring finger and CHY zinc finger domain containing 1 antibody, ring finger and CHY zinc finger domain containing 1 L homeolog antibody, RCHY1 antibody, Rchy1 antibody, rchy1 antibody, rchy1.L antibody
- 背景
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RCHY1 has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53.The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZNF363, hARNIP, PIRH2E, PIRH2F
Protein Interaction Partner: MEOX2, NOTCH2NL, UBASH3B, KRTAP9-2, LIMS2, SEMA4C, WDR74, ADAMTSL4, RCHY1, PGLS, KLHL41, MDM2, TAOK2, TP53, UBC, RNF2, HOXA2, YWHAE, CDK9, DCUN1D5, RILP, TMBIM1, CHD8, USP28, C19orf80, RBM38, NLK, TMEM14C, AIG1, SERTAD1, CHEK2, PRDX4, RAB11A, FADS6, TMEM1
Protein Size: 200 - 分子量
- 23 kDa
- 基因ID
- 25898
- NCBI登录号
- NM_001008925, NP_001008925
- UniProt
- Q96PM5
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