RCHY1 抗体
(Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| RCHY1 抗体 | 人, 大鼠 | 小鼠 Monoclonal |
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| RCHY1 抗体 (AA 1-261) | 人 | 兔 Polyclonal |
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| Recombinant RCHY1 抗体 | 人 | 兔 Monoclonal |
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| RCHY1 抗体 (AA 1-252) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 36-85) | 人, 大鼠, Cow, 马, 兔, 绵羊, 猴 | 兔 Polyclonal |
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| RCHY1 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 | 人 | 兔 Monoclonal |
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| RCHY1 抗体 (AA 1-100) | 人 | 小鼠 Monoclonal |
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| RCHY1 抗体 (AA 31-130) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) (AbBy Fluor® 555) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) (AbBy Fluor® 488) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) (HRP) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) (FITC) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) (Cy7) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) (AbBy Fluor® 750) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) (Biotin) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) (Cy5.5) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) (Cy5) | 人 | 兔 Polyclonal |
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| RCHY1 抗体 (AA 31-130) (Cy3) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
2 references - 适用
- 人, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1H10
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-261
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- KD Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 25GB3545
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-252
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5D12
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 555
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 488
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy7
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 750
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5.5
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 31-130
Latest Publications for our RCHY1 抗体
: "p27kip1 Expression in non-small cell lung cancer is not an independent prognostic factor." in: Anticancer research, Vol. 30, Issue 9, pp. 3699-704, (2010) (PubMed).
: "The Pirh2-keratin 8/18 interaction modulates the cellular distribution of mitochondria and UV-induced apoptosis." in: Cell death and differentiation, Vol. 16, Issue 6, pp. 826-37, (2009) (PubMed).
: "Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains." in: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 21955-70, (2009) (PubMed).
: "Molecular basis of Pirh2-mediated p53 ubiquitylation." in: Nature structural & molecular biology, Vol. 15, Issue 12, pp. 1334-42, (2008) (PubMed).
: "Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53." in: The EMBO journal, Vol. 26, Issue 13, pp. 3062-74, (2007) (PubMed).
: "Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells." in: Experimental cell research, Vol. 312, Issue 17, pp. 3370-8, (2006) (PubMed).
: "Activation of p53 in cervical cancer cells by human papillomavirus E6 RNA interference is transient, but can be sustained by inhibiting endogenous nuclear export-dependent p53 antagonists." in: Cancer research, Vol. 66, Issue 24, pp. 11817-24, (2006) (PubMed).
: "Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3." in: The EMBO journal, Vol. 24, Issue 9, pp. 1739-49, (2005) (PubMed).
: "Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer." in: Journal of the National Cancer Institute, Vol. 96, Issue 22, pp. 1718-21, (2004) (PubMed).
: "The Pirh2-keratin 8/18 interaction modulates the cellular distribution of mitochondria and UV-induced apoptosis." in: Cell death and differentiation, Vol. 16, Issue 6, pp. 826-37, (2009) (PubMed).
: "Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains." in: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 21955-70, (2009) (PubMed).
: "Molecular basis of Pirh2-mediated p53 ubiquitylation." in: Nature structural & molecular biology, Vol. 15, Issue 12, pp. 1334-42, (2008) (PubMed).
: "Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53." in: The EMBO journal, Vol. 26, Issue 13, pp. 3062-74, (2007) (PubMed).
: "Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells." in: Experimental cell research, Vol. 312, Issue 17, pp. 3370-8, (2006) (PubMed).
: "Activation of p53 in cervical cancer cells by human papillomavirus E6 RNA interference is transient, but can be sustained by inhibiting endogenous nuclear export-dependent p53 antagonists." in: Cancer research, Vol. 66, Issue 24, pp. 11817-24, (2006) (PubMed).
: "Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3." in: The EMBO journal, Vol. 24, Issue 9, pp. 1739-49, (2005) (PubMed).
: "Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer." in: Journal of the National Cancer Institute, Vol. 96, Issue 22, pp. 1718-21, (2004) (PubMed).
Aliases for RCHY1 抗体
ring finger and CHY zinc finger domain containing 1 (RCHY1) 抗体ring finger and CHY zinc finger domain containing 1 (Rchy1) 抗体
ring finger and CHY zinc finger domain containing 1 (rchy1) 抗体
ring finger and CHY zinc finger domain containing 1 L homeolog (rchy1.L) 抗体
ARNIP 抗体
arnip 抗体
CHIMP 抗体
chimp 抗体
harnip 抗体
PIRH2 抗体
Pirh2 抗体
pirh2 抗体
PRO1996 抗体
pro1996 抗体
RCHY1 抗体
RNF199 抗体
rnf199 抗体
wu:fb37e07 抗体
Zfp363 抗体
zgc:101128 抗体
ZNF363 抗体
Znf363 抗体
znf363 抗体
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