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PKC zeta 抗体 (N-Term)

The 兔多克隆 anti-PKC zeta antibody (ABIN2775614) specifically detects PKC zeta in WB. The antibody is reactive with 人, 小鼠, 大鼠, 兔, Cow, 犬, 马和豚鼠 samples.

Rabbit Anti-PRKCZ Antibody Formalin Fixed Paraffin Embedded Tissue: Human Testis Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:600 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (PKC zeta 抗体 (N-Term))

IHC

2 images

产品编号 ABIN2775614

发货至: 中国

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Quick Overview for PKC zeta 抗体 (N-Term) (ABIN2775614)

抗原

See all PKC zeta (PRKCZ) 抗体

PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

适用

人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This PKC zeta antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product PRKCZ Primary Antibody

抗原表位
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1

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1

1
N-Term

原理

PRKCZ Antibody - N-terminal region

序列

MDSVMPSQEP PVDDKNEDAD LPSEETDGIA YISSSRKHDS IKDDSEDLKP

预测反应

Cow: 77%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 92%, Rabbit: 79%, Rat: 92%

产品特性

This is a rabbit polyclonal antibody against PRKCZ. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCZ
anti-Protein Kinase C, zeta (PRKCZ) (AA 453-592) antibody
PRKCZ 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (AA 165-255) antibody
PRKCZ 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D1 unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (Cytoplasmic Domain) antibody
PRKCZ 适用: 人 IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) antibody
PRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Monoclonal R14-K unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (AA 166-197), (N-Term) antibody
PRKCZ 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01027 unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (N-Term) antibody
PRKCZ 适用: 人 IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (pThr410) antibody
PRKCZ 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (C-Term) antibody
PRKCZ 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (pThr560) antibody
PRKCZ 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB890 unconjugated Recombinant Antibody

anti-Protein Kinase C, zeta (PRKCZ) antibody
PRKCZ 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4195 unconjugated Recombinant Antibody

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109312

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
抗原

PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

别名

PRKCZ

背景

Background Information: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: Protein kinase C, zeta
Alternative Symbols: PKC2, PKC-ZETA
Protein Name: Protein kinase C zeta type

分子量

45kDa

基因ID

5590

NCBI登录号

NP_001028753

UniProt

Q05513

途径

NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling