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- 抗原 See all MLH3 抗体
- MLH3 (MutL Homolog 3 (MLH3))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MLH3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SMQVLQQVDN KFIACLMSTK TEENGEADSY EKQQAQGSGR KKLLSSTLIP
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MLH3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MLH3
- Top Product
- Discover our top product MLH3 Primary Antibody
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anti-MutL Homolog 3 (MLH3) (Internal Region) antibody
MLH3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 3 (MLH3) (C-Term) antibodyVerified MLH3 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-MutL Homolog 3 (MLH3) antibodyMLH3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 3 (MLH3) (AA 1188-1237) antibodyMLH3 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 3 (MLH3) (AA 1180-1429) antibodyMLH3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 3 (MLH3) (AA 521-570) antibodyMLH3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1429 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MLH3 (MutL Homolog 3 (MLH3))
- 别名
- MLH3 (MLH3 产品)
- 别名
- AV125803 antibody, BB126472 antibody, MGC80774 antibody, MLH3 antibody, HNPCC7 antibody, mutL homolog 3 antibody, mutL homolog 3 L homeolog antibody, Mlh3 antibody, mlh3.L antibody, MLH3 antibody, mlh3 antibody
- 背景
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This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. MLH3 functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Alias Symbols: HNPCC7, MGC138372
Protein Interaction Partner: MLH1, MYC, FAN1, AR, MLH3, MSH4,
Protein Size: 1429 - 分子量
- 161 kDa
- 基因ID
- 27030
- NCBI登录号
- NM_014381, NP_055196
- UniProt
- Q2M1Z1
- 途径
- Chromatin Binding
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