电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

TWEAK 抗体 (N-Term)

TNFSF12 适用: 人, 小鼠, 大鼠, 马, 犬, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774826
发货至: 中国
  • 抗原 See all TWEAK (TNFSF12) 抗体
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    抗原表位
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, 马, 犬, 兔, 斑马鱼
    宿主
    • 44
    • 11
    • 10
    • 2
    克隆类型
    • 55
    • 11
    • 1
    多克隆
    标记
    • 38
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TWEAK antibody is un-conjugated
    应用范围
    • 39
    • 26
    • 17
    • 13
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB)
    序列
    LGLLLAVVSL GSRASLSAQE PAQEELVAEE DQDPSELNPQ TEESQDPAPF
    预测反应
    Dog: 79%, Horse: 93%, Human: 100%, Mouse: 83%, Rabbit: 83%, Rat: 86%, Zebrafish: 82%
    产品特性
    This is a rabbit polyclonal antibody against TNFSF12. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human TNFSF12
    Top Product
    Discover our top product TNFSF12 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 249 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    别名
    TNFSF12 (TNFSF12 产品)
    别名
    APO3L antibody, DR3LG antibody, TWEAK antibody, Apo3l antibody, Dr3l antibody, Dr3lg antibody, Tweak antibody, TNF superfamily member 12 antibody, tumor necrosis factor (ligand) superfamily, member 12 antibody, TNFSF12 antibody, Tnfsf12 antibody
    背景
    TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: APO3L, DR3LG, MGC129581, MGC20669, TWEAK
    Protein Interaction Partner: DDIT3, TNFSF13B, LYN, OTUB1, TRAF2, BIRC2, AGGF1, TNFRSF12A, TNFRSF25,
    Protein Size: 249
    分子量
    17 kDa
    基因ID
    8742
    NCBI登录号
    NM_003809, NP_003800
    UniProt
    O43508
    途径
    Apoptosis
You are here:
客服