c-Rel 抗体 (N-Term)
Quick Overview for c-Rel 抗体 (N-Term) (ABIN2774658)
抗原
See all c-Rel 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ASGAYNPYIE IIEQPRQRGM RFRYKCEGRS AGSIPGEHST DNNRTYPSIQ
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交叉反应
- 小鸡, 人, 小鼠
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against REL. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human REL
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应用备注
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WB Suggested Anti-REL Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: Hela cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 619 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- c-Rel (REL proto-oncogene (c-Rel))
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别名
- REL
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背景
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REL is a member of the Rel/NFKB family, which also includes RELA, RELB, NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor.The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-174 CN414487.1 2-175 175-2323 X75042.1 128-2276 2324-2457 BX111941.1 575-708 2458-2592 AA279919.1 1-135 c
Alias Symbols: C-Rel
Protein Interaction Partner: NFKB2, REXO1L6P, C12orf75, TRIM74, RAB41, BARHL2, SEC14L4, NUDT14, ZDHHC24, NEIL2, CPNE2, C9orf72, STRA13, TTC21A, FUT11, ZNF564, ZNF550, PATE1, TSTD2, ZNF417, ZNF572, GLYCTK, EGLN3, RIPPLY1, ZNF765, ATPAF2, SLC39A13, BMF, KRTAP9-4, CEP19, VPS25, MIEN1, P
Protein Size: 619 -
分子量
- 68 kDa
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基因ID
- 5966
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NCBI登录号
- NM_002908, NP_002899
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UniProt
- Q04864
抗原
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