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ACE2 抗体 (Middle Region)

Name: ACE2 抗体 (Middle Region)
SKU: ABIN2774060
Availability: OutOfStock

ACE2 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

Immunohistochemistry (IHC) image for anti-Angiotensin I Converting Enzyme 2 (ACE2) (Middle Region) antibody (ABIN2774060)

IHC

1 image

(1 reference)

产品编号 ABIN2774060

发货至: 中国

Datasheet as PDF

抗原 See all ACE2 抗体

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
抗原表位
16

14

12

9

9

9

6

5

5

4

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Middle Region

适用

人, 小鼠, 大鼠, Pig, 犬, Cow, 豚鼠, 马, 兔
宿主
129

20

6
兔
Compatible Secondaries
克隆类型
108

47
多克隆
标记
80

16

10

8

5

4

3

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1
This ACE2 antibody is un-conjugated
应用范围
122

68

49

36

36

19

17

11

11

11

10

6

3

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

FVTAPKNVSD IIPRTEVEKA IRMSRSRIND AFRLNDNSLE FLGIQPTLGP

预测反应

Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 86%, Rat: 93%

产品特性

This is a rabbit polyclonal antibody against ACE2. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human ACE2

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ACE2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal AC18F unconjugated

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ACE2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

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ACE2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

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ACE2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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ACE2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (N-Term) antibody
Verified ACE2 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated

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ACE2 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM47 unconjugated Recombinant Antibody

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 773-805) antibody
ACE2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 140-172) antibody
ACE2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 805 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Mak, Chin, Cunningham, Habib, Torresi, Sharland, Alexander, Angus, Herath: "ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 23, Issue 9, pp. 1434-43, (2015) (PubMed).
抗原

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

别名

ACE2 (ACE2 产品)

别名

ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, ACEH antibody, 2010305L05Rik antibody, zgc:92514 antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme 2 antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antibody, ACE antibody, ACE2 antibody, Ace2 antibody, ace2 antibody

背景

ACE2 belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This protein catalyzes the cleavage of angiotensin I into angiotensin 1-9. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACEH, DKFZP434A014
Protein Interaction Partner: ACE2, AGT, CALM1, NTS, GHRL,
Protein Size: 805

分子量

89 kDa

基因ID

59272

NCBI登录号

NM_021804, NP_068576

UniProt

Q9BYF1

途径

ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour