RFC5 抗体 (N-Term)
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- 抗原 See all RFC5 抗体
- RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Saccharomyces cerevisiae, Cow, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFC5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- METSALKQQE QPAATKIRNL PWVEKYRPQT LNDLISHQDI LSTIQKFINE
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Yeast: 90%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against RFC5. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RFC5
- Top Product
- Discover our top product RFC5 Primary Antibody
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anti-Replication Factor C (Activator 1) 5, 36.5kDa (RFC5) (AA 1-340) antibody
RFC5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-Replication Factor C (Activator 1) 5, 36.5kDa (RFC5) (AA 170-200) antibodyRFC5 适用: 人, 大鼠 WB, FACS 宿主: 兔 Polyclonal RB17319 unconjugated
anti-Replication Factor C (Activator 1) 5, 36.5kDa (RFC5) (N-Term) antibodyRFC5 适用: 人, 犬, 豚鼠, 马, 猴, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Replication Factor C (Activator 1) 5, 36.5kDa (RFC5) antibodyRFC5 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Replication Factor C (Activator 1) 5, 36.5kDa (RFC5) (AA 1-340) antibodyRFC5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Replication Factor C (Activator 1) 5, 36.5kDa (RFC5) (AA 181-340) antibodyRFC5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 340 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))
- 别名
- RFC5 (RFC5 产品)
- 别名
- zgc:110313 antibody, 2610020K06Rik antibody, 2610209F07Rik antibody, 36.5kDa antibody, 36kDa antibody, Recc5 antibody, RFC36 antibody, replication factor C (activator 1) 5 antibody, replication factor C subunit 5 antibody, replication factor C subunit 5 L homeolog antibody, rfc5 antibody, Rfc5 antibody, RFC5 antibody, rfc5.L antibody
- 背景
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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. RFC5 is the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: MGC1155, RFC36
Protein Interaction Partner: NAB2, XIAP, TRIM38, HUWE1, RFC4, SUMO2, PCNA, UBC, RPA3, RPA2, RPA1, EED, FBXO6, MMS19, VCP, ECT2, MDC1, MTMR2, RFC3, RFC2, RFC1, CAND1, CUL3, NEDD8, HDGF, SMARCAD1, PIDD1, MYC, RPAP3, MEPCE, RUVBL2, LRIF1, COPS6, MED31, RBM48, UNC119, EEF1A1, RAD17, BRD4
Protein Size: 340 - 分子量
- 38 kDa
- 基因ID
- 5985
- NCBI登录号
- NM_007370, NP_031396
- UniProt
- P40937
- 途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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