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SERPINB5 抗体

SERPINB5 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272300
发货至: 中国
  • 抗原 See all SERPINB5 抗体
    SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
    适用
    • 74
    • 37
    • 31
    • 17
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 67
    • 6
    • 1
    克隆类型
    • 67
    • 7
    多克隆
    标记
    • 40
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SERPINB5 antibody is un-conjugated
    应用范围
    • 67
    • 32
    • 29
    • 29
    • 14
    • 14
    • 13
    • 13
    • 8
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of Maspin protein. (region surrounding Thr118)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product SERPINB5 Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
    别名
    SERPINB5 / Maspin (SERPINB5 产品)
    别名
    1110036M19Rik antibody, AI462524 antibody, AI646751 antibody, Maspin antibody, PI-5 antibody, Spi7 antibody, ovalbumin antibody, PI5 antibody, maspin antibody, Pi5 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 5 antibody, serpin family B member 5 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 5 S homeolog antibody, Serpinb5 antibody, SERPINB5 antibody, serpinb5.S antibody
    背景
    Maspin is structurally a serine protease inhibitor (serpin) that was initially isolated from normal human mammary epithelial cells. Serpins are a family of proteins that inhibit chymotrypsin-like serine proteinases. Serpins control activated proteinases and several are involved in the regulation of cell death. Maspin is found in the extracellular matrix and at the plasma membrane. Maspin has been shown to act at the cell surface to block cell motility and inhibit invasion of breast and prostate cancer cells. Maspin is present in normal mammary epithelial cells but is absent in many tumor cell lines, yet no major structural alterations of the Maspin gene have been identified in tumor cells. Similarly, Maspin is expressed in normal prostate cells and downregulated or absent in prostate tumor cells.Synonyms: PI-5, PI5, Peptidase inhibitor 5, Protease inhibitor 5, Serpin B5
    分子量
    approx. 42 kDa
    基因ID
    5268
    NCBI登录号
    NP_002630
    UniProt
    P36952
    途径
    p53 Pathway
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