CYP24A1 抗体
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- 抗原 See all CYP24A1 抗体
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP24A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of CYP24A1 protein. (region surrounding Arg439)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CYP24A1 Primary Antibody
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anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (AA 351-450) antibody
CYP24A1 适用: 人, 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (AA 415-514) antibodyCYP24A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (AA 36-448) antibodyCYP24A1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (AA 153-514) antibodyCYP24A1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (AA 260-514) antibodyCYP24A1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (AA 415-514) antibodyCYP24A1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (C-Term) antibodyCYP24A1 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (Internal Region) antibodyVerified CYP24A1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (Center) antibodyCYP24A1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (AA 37-250) antibodyCYP24A1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
- 别名
- CYP24A1 (CYP24A1 产品)
- 别名
- CP24 antibody, CYP24 antibody, HCAI antibody, P450-CC24 antibody, 24-OHase antibody, Cyp24 antibody, 25-hydroxyvitaminD324-hydroxylase antibody, VITD12 antibody, CP450CC24 antibody, cytochrome P450 family 24 subfamily A member 1 antibody, cytochrome P450, family 24, subfamily a, polypeptide 1 antibody, cytochrome P450, family 24, subfamily A, polypeptide 1 antibody, CYP24A1 antibody, Cyp24a1 antibody
- 背景
- P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. P450 enzymes can be classified, based on their sequence similarities, into distinct subfamilies, which include CYP1A and CYP2A. The P450 family member, CYP19, catalyzes the conversion of C19 steroids to estrogens in various tissues, including placenta, gonads, adipose tissue, skin and brain. P450 cholesterol 7a-hydroxylase, CYP7A1, is the rate limiting enzyme of bile acid synthesis in the liver, and its expression is mediated by the bile acid receptor FXR. CYP27A1 catalyzes vitamin D 25-hydroxylation and is localized to the mitochondria in kidney and liver. Overexpression of CYP24 (encoding vitamin D 24 hydroxylase) is likely to lead to abrogation of growth control mediated by vitamin D.Synonyms: 24-OHase, 25-dihydroxyvitamin D(3) 24-hydroxylase, CYP24, Cytochrome P450 24A1, Cytochrome P450-CC24, Vitamin D3 24-hydroxylase, mitochondrial 1
- 分子量
- approx. 38 kDa
- 基因ID
- 1591
- NCBI登录号
- NP_000773
- UniProt
- Q07973
- 途径
- Metabolism of Steroid Hormones and Vitamin D
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