CYP24A1 抗体 (AA 153-514)
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- 抗原 See all CYP24A1 抗体
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
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抗原表位
- AA 153-514
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP24A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: cytochrome P450, family 24, subfamily A, polypeptide 1
Protein Name: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human CYP24A1 recombinant protein (Position: E153-R514). Human CYP24A1 shares 86.2% amino acid (aa) sequence identity with both mouse and rat CYP24A1.
- 亚型
- IgG
- Top Product
- Discover our top product CYP24A1 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
- 别名
- CYP24A1 (CYP24A1 产品)
- 别名
- CP24 antibody, CYP24 antibody, HCAI antibody, P450-CC24 antibody, 24-OHase antibody, Cyp24 antibody, 25-hydroxyvitaminD324-hydroxylase antibody, VITD12 antibody, CP450CC24 antibody, cytochrome P450 family 24 subfamily A member 1 antibody, cytochrome P450, family 24, subfamily a, polypeptide 1 antibody, cytochrome P450, family 24, subfamily A, polypeptide 1 antibody, CYP24A1 antibody, Cyp24a1 antibody
- 背景
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. And this mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: 1 25 @dihydroxyvitamin D3 24 hydroxylase antibody|1 25 dihydroxyvitamin D(3) 24 hydroxylase antibody|1 antibody|1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial antibody|24 ohase antibody|24-OHase antibody|25-dihydroxyvitamin D(3) 24-hydroxylase antibody|CP 24 antibody|CP24 antibody|CP24A_HUMAN antibody|CYP 24 antibody|CYP24 antibody|CYP24A1 antibody|Cytochrome P450 24A1 antibody| Cytochrome P450 24A1 mitochondrial antibody| cytochrome P450 CC24 antibody|Cytochrome P450 family 24 antibody|Cytochrome P450 family 24 subfamily A polypeptide 1 antibody|Cytochrome P450 subfamily XXIV antibody|Cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) antibody|Cytochrome P450-CC24 antibody|EC 1.14.13.n4 antibody|Exo mitochondrial protein antibody|HCAI antibody|MGC126273 antibody| MGC126274 antibody|mitochondrial antibody|P450 CC24 antibody|Vitamin D 24 hydroxylase antibody|Vitamin D(3) 24 hydroxylase antibody| Vitamin D(3) 24-hydroxylase antibody - 基因ID
- 1591
- UniProt
- Q07973
- 途径
- Metabolism of Steroid Hormones and Vitamin D
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