DGKD 抗体
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Quick Overview for DGKD 抗体 (ABIN272240)
抗原
See all DGKD 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of DGK-δ protein. (region surrounding Ser66)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Diacylglycerol Kinase, delta 130kDa (DGKD) (N-Term) antibody
DGKD 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Diacylglycerol Kinase, delta 130kDa (DGKD) (AA 1061-1091), (C-Term) antibodyDGKD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3865 unconjugated
anti-Diacylglycerol Kinase, delta 130kDa (DGKD) (N-Term) antibodyDGKD 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Diacylglycerol Kinase, delta 130kDa (DGKD) (AA 449-498) antibodyDGKD 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Diacylglycerol Kinase, delta 130kDa (DGKD) (C-Term) antibodyDGKD 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DGKD (Diacylglycerol Kinase, delta 130kDa (DGKD))
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别名
- DAG Kinase delta
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背景
- Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DAG) to produce phosphatidic acid. DAG and phosphatidic acid are lipids that act as second messengers in signaling cascades. DGK-α influences cell activation and secretion of lethal exosomes, which in turn control cell death. DGK-β is abundant in restricted brain regions such as the caudate putamen and olfactory tubercle. DGK-γ encodes full-length and truncated transcripts that are present in a range of human tissues, with greatest expression observed in retina. DGK-δ is most abundant in skeletal muscle. DGK-ε shows specificity for arachidonylcontaining diacylglycerol and is expressed predominantly in testis. DGK-θ is most abundant in the cerebellum and hippocampus. DGK-ι is present in brain and retina as a predominant transcript of more than 12 kb, including a long 3-prime untranslated region, with additional low abundance transcripts of 9.5 and 7.5 kb. DGK-η is closely related to DGK-δ. DGK-ζ is most abundant in brain and muscle. DGKs have structural motifs that play regulatory roles, and these motifs form the basis for dividing the DGKs into five subtypes.Synonyms: DGK-delta, DGKD, Diacylglycerol kinase delta, Diglyceride kinase delta, KIAA0145
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分子量
- approx. 135 kDa
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基因ID
- 8527
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NCBI登录号
- NP_003639
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UniProt
- Q16760
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途径
- EGFR Signaling Pathway
抗原
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