GRK6 抗体
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- 抗原 See all GRK6 抗体
- GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRK6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 特异性
- This antibody detects endogenous levels of GRK 6 protein. (region surrounding asn22)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product GRK6 Primary Antibody
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anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 71-170) antibody
GRK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 382-417), (C-Term) antibodyGRK6 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 71-170) antibodyGRK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 71-170) antibodyGRK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8D4 unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (N-Term) antibodyGRK6 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 1-170) antibodyGRK6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 1-170) antibodyGRK6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 1-589) antibodyGRK6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (N-Term) antibodyGRK6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 186-448) antibodyGRK6 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))
- 别名
- GRK6 (GRK6 产品)
- 别名
- MGC83187 antibody, GRK6 antibody, GPRK6 antibody, Gprk6 antibody, G protein-coupled receptor kinase 6 antibody, G protein-coupled receptor kinase 6 S homeolog antibody, GRK6 antibody, grk6.S antibody, grk6 antibody, Grk6 antibody
- 背景
- Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonistmediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first are the second messenger-regulated kinases such as c-AMP dependent protein kinase A and protein kinase C. The second are the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase, GRK 1, two forms of β-adrenergic receptor kinase, GRK 2 (βARK, βARK1) and GRK 3 (βARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.Synonyms: G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6, GPRK6
- 分子量
- approx. 65 kDa
- 基因ID
- 2870
- NCBI登录号
- NP_001004105
- UniProt
- P43250
- 途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Negative Regulation of Transporter Activity
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