GRK6 抗体 (N-Term)
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北京 101111
Quick Overview for GRK6 抗体 (N-Term) (ABIN7184455)
抗原
See all GRK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- GRK6 Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from N-terminal of Human GRK6.
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亚型
- IgG
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anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 71-170) antibody
GRK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 382-417), (C-Term) antibodyGRK6 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 71-170) antibodyGRK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8D4 unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 71-170) antibodyGRK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) antibodyKD Validated GRK6 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4870 unconjugated Recombinant Antibody
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 1-589) antibodyGRK6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 1-170) antibodyGRK6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 1-170) antibodyGRK6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (N-Term) antibodyGRK6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) antibodyGRK6 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1500 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))
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别名
- GRK6
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背景
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Background: Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis By similarity. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
Benovic J.L., J. Biol. Chem. 268:19521-19527(1993).
Haribabu B., Proc. Natl. Acad. Sci. U.S.A. 90:9398-9402(1993).
Stoffel R.H., J. Biol. Chem. 269:27791-27794(1994).Aliases: FLJ32135 antibody, G protein coupled receptor kinase 6 antibody, G protein coupled receptor kinase GRK6 antibody, G protein-coupled receptor kinase 6 antibody, G protein-coupled receptor kinase GRK6 antibody, Gprk6 antibody, Grk6 antibody, GRK6_HUMAN antibody
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UniProt
- P43250
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Negative Regulation of Transporter Activity
抗原
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