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GAS41 抗体

适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272151
发货至: 中国
  • 抗原 See all GAS41 products
    GAS41 (YEATS Domain Containing 4)
    适用
    • 51
    • 43
    • 16
    • 15
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    人, 小鼠
    宿主
    • 57
    • 9
    克隆类型
    • 59
    • 7
    多克隆
    标记
    • 28
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GAS41 antibody is un-conjugated
    应用范围
    • 51
    • 24
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of GAS41 protein. (region surrounding Arg32)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
  • 应用备注
    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    GAS41 (YEATS Domain Containing 4)
    别名
    YEATS4 (GAS41 产品)
    别名
    4930573H17Rik antibody, B230215M10Rik antibody, GAS41 antibody, NUBI-1 antibody, YAF9 antibody, YEATS4 antibody, NuBI-1 antibody, RGD1305741 antibody, zgc:100841 antibody, MGC89432 antibody, CG9207 antibody, Dmel\\CG9207 antibody, dGas41 antibody, GB13136 antibody, GLIOMAS 41 antibody, K2N11.8 antibody, K2N11_8 antibody, TAF14B antibody, TBP-ASSOCIATED FACTOR 14B antibody, NV13456 antibody, YEATS domain containing 4 antibody, YEATS domain containing 4 S homeolog antibody, CG9207 gene product from transcript CG9207-RA antibody, YEATS domain-containing protein 4 antibody, YEATS family protein antibody, Gas41 antibody, gas41 homologue, putative antibody, putative gas41 antibody, YEATS4 antibody, Yeats4 antibody, yeats4.S antibody, yeats4 antibody, Gas41 antibody, LOC412705 antibody, GAS41 antibody, Chro.20029 antibody, PB300718.00.0 antibody, PCHAS_122420 antibody, Smp_070760 antibody, LOC100121822 antibody
    背景
    Gene amplification is associated with tumor stage and progression in human gliomas. Several amplified loci are identified and comprise multiple genes. The glioma amplified sequence 41 (GAS41) is an evolutionarily conserved eukaryotic protein found in diverse species. GAS41 is related to the AF-9 and ENL proteins, which are putative transcription factors in some acute leukemias,and interacts with a component of the nuclear matrix, NuMA, in interphase cells. GAS41 has a dotted staining pattern in interphase nuclei and a uniform distribution in mitotic cells. GAS41 is ubiquitously expressed, with the highest levels of expression in human brain. In neuroblastoma, GAS41 is located in the nucleoli, but not in the nucleoplasm. GAS41 also binds to the MLL fusion partner AF-10, which is involved in two distinct chromosomal translocations associated with hematologic malignancy. In addition, GAS41 interacts with INI1 (integrase interactor 1), which is a human homolog of the yeast Snf5 protein, a component of the SWI/SNF complex. The GAS41 gene maps to human chromosome 12q13-q15.Synonyms: GAS41, Glioma-amplified sequence 41, NuBI-1, NuBI1, NuMA-binding protein 1, YEATS domain-containing protein 4
    分子量
    approx. 42 kDa
    基因ID
    8089
    NCBI登录号
    NP_006521
    UniProt
    O95619
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