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Estrogen Receptor alpha 抗体

ESR1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 1B1 unconjugated
产品编号 ABIN2720526
发货至: 中国
  • 抗原 See all Estrogen Receptor alpha (ESR1) 抗体
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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    小鼠
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    单克隆
    标记
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    This Estrogen Receptor alpha antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1
    纯化方法
    Purified from mouse ascites fluids by affinity chromatography
    免疫原
    Full length human recombinant protein of human ESR1(NP_000116) produced in HEK293T cell.
    克隆位点
    1B1
    亚型
    IgG2b
    Top Product
    Discover our top product ESR1 Primary Antibody
  • 应用备注
    WB 1:2000, IHC 1:150,
    说明

    The concentration of the product may vary between diferrent lots.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5-1.0 mg/mL
    缓冲液
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Andreani, Bartolacci, Wijnant, Crinelli, Bianchi, Magnani, Hysi, Iezzi, Amici, Marchini: "Resveratrol fuels HER2 and ERα-positive breast cancer behaving as proteasome inhibitor." in: Aging, Vol. 9, Issue 2, pp. 508-523, (2017) (PubMed).

    Sun, Gu, Xia, Zhong, Song, Guo: "Significance of estrogen receptor subtypes in breast tumorigenesis and progression." in: Tumour biology, Vol. 35, Issue 9, pp. 9111-7, (2014) (PubMed).

  • 抗原
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    别名
    ESR1 (ESR1 产品)
    别名
    LOC398734 antibody, AA420328 antibody, AU041214 antibody, ER-alpha antibody, ER[a] antibody, ERa antibody, ERalpha antibody, ESR antibody, Estr antibody, Estra antibody, Nr3a1 antibody, NR3A1 antibody, eralpha antibody, zfER[a] antibody, ER antibody, ESRA antibody, ESTRR antibody, Era antibody, akap12 antibody, cb27 antibody, esr1 antibody, fb72g12 antibody, id:ibd1202 antibody, sb:cb27 antibody, si:ch73-192g21.1 antibody, wu:fb72g12 antibody, wu:fc21c03 antibody, Esr antibody, RNESTROR antibody, ERALPHA antibody, er antibody, esr antibody, nr3a1 antibody, XER antibody, era antibody, esra antibody, ERbeta antibody, xesr-1 antibody, xlERalpha1 antibody, xlERalpha2 antibody, ESR1 antibody, estrogen receptor 1 L homeolog antibody, estrogen receptor 1 (alpha) antibody, estrogen receptor 1 antibody, A kinase (PRKA) anchor protein 12b antibody, esr1.L antibody, Esr1 antibody, ESR1 antibody, esr1 antibody, akap12b antibody
    背景
    This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
    分子量
    66 kDa
    基因ID
    2099
    NCBI登录号
    NM_000125
    HGNC
    2099
    途径
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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