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Estrogen Receptor alpha 抗体 (AA 2-185)

Name: Estrogen Receptor alpha 抗体 (AA 2-185)
Brand: antibodies-online
SKU: ABIN6939348
Availability: OutOfStock

ESR1 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal ER506 unconjugated

Western Blot Analysis of human MCF-7 cell lysate using Estrogen Receptor alpha Mouse Monoclonal Antibody (ER506). (Estrogen Receptor alpha 抗体 (AA 2-185))

Analysis of Protein Array containing more than 19,000 full-length human proteins using Estrogen Receptor, alpha Mouse Monoclonal Antibody (ER506). (Estrogen Receptor alpha 抗体 (AA 2-185))

PAr

Flow Cytometry for human ER-alpha on MCF-7 cells. (Estrogen Receptor alpha 抗体 (AA 2-185))

FACS

Formalin-fixed, paraffin-embedded human Endometrium stained with Estrogen Receptor alpha Mouse Monoclonal Antibody (ER506). (Estrogen Receptor alpha 抗体 (AA 2-185))

IHC

SDS-PAGE Analysis Purified Estrogen Receptor alpha Mouse Monoclonal Antibody (ER506). (Estrogen Receptor alpha 抗体 (AA 2-185))

SDS

5 images

产品编号 ABIN6939348

发货至: 中国

Datasheet as PDF

抗原 See all Estrogen Receptor alpha (ESR1) 抗体

Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
抗原表位
32

30

26

23

21

21

20

16

16

16

16

15

15

15

13

12

11

10

9

9

8

7

7

7

6

6

6

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
AA 2-185
适用
473

173

167

19

18

10

7

6

5

4

3

3

3

2

1

1
人
宿主
385

96

2

1
小鼠
Compatible Secondaries
克隆类型
364

122
单克隆
标记
222

35

23

22

18

15

15

15

15

15

15

10

8

8

8

8

8

4

4

4

4

4

4

1

1
This Estrogen Receptor alpha antibody is un-conjugated
应用范围
369

172

141

111

94

90

80

67

39

31

24

15

10

7

6

6

5

2

2

2

2

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)

特异性

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.

纯化方法

Purified by Protein A/G

免疫原

Recombinant fragment (around aa 2-185) of human Estrogen Receptor alpha protein (exact sequence is proprietary)

克隆位点

ER506

亚型

IgG1 kappa

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anti-Estrogen Receptor 1 (ESR1) antibody
ESR1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ESR1-1904 unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibody
ESR1 适用: 人, 大鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6A6E8 unconjugated

anti-Estrogen Receptor 1 (ESR1) (pSer167) antibody
ESR1 适用: 人, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (C-Term) antibody
ESR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibody
ESR1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB33807 unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibody
ESR1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (pSer118) antibody
ESR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 331-360) antibody
ESR1 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 233-483) antibody
ESR1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Positive Control: MCF-7 cells. Breast or Endometrial Carcinoma.
Known Application: Flow Cytometry (0.5-1 μg/million cells), ,Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) ,Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

限制

仅限研究用
浓度

200 μg/mL

缓冲液

10 mM PBS with 0.05 % BSA & 0.05 % azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-80 °C

储存方法

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

有效期

24 months
抗原

Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

别名

ESR1 (ESR1 产品)

别名

LOC398734 antibody, AA420328 antibody, AU041214 antibody, ER-alpha antibody, ER[a] antibody, ERa antibody, ERalpha antibody, ESR antibody, Estr antibody, Estra antibody, Nr3a1 antibody, NR3A1 antibody, eralpha antibody, zfER[a] antibody, ER antibody, ESRA antibody, ESTRR antibody, Era antibody, akap12 antibody, cb27 antibody, esr1 antibody, fb72g12 antibody, id:ibd1202 antibody, sb:cb27 antibody, si:ch73-192g21.1 antibody, wu:fb72g12 antibody, wu:fc21c03 antibody, Esr antibody, RNESTROR antibody, ERALPHA antibody, er antibody, esr antibody, nr3a1 antibody, XER antibody, era antibody, esra antibody, ERbeta antibody, xesr-1 antibody, xlERalpha1 antibody, xlERalpha2 antibody, ESR1 antibody, estrogen receptor 1 L homeolog antibody, estrogen receptor 1 (alpha) antibody, estrogen receptor 1 antibody, A kinase (PRKA) anchor protein 12b antibody, esr1.L antibody, Esr1 antibody, ESR1 antibody, esr1 antibody, akap12b antibody

分子量

~67kDa

基因ID

2099

UniProt

P03372

途径

Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly