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Estrogen Receptor alpha 抗体

The 小鼠 单克隆 anti-Estrogen Receptor alpha antibody (Clone 119-13) (ABIN7455134) specifically detects Estrogen Receptor alpha in WB, IHC, FACS, ICC 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7455134
发货至: 中国
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Quick Overview for Estrogen Receptor alpha 抗体 (ABIN7455134)

抗原

See all Estrogen Receptor alpha (ESR1) 抗体
Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Estrogen Receptor alpha antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

克隆位点

119-13
  • 原理

    Mouse anti-Estrogen Receptor Alpha Monoclonal Antibody [119-13]

    纯化方法

    Purified

    亚型

    IgG1
  • 应用备注

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 6 μL/1 mg lysate

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 01:01,00

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1000 μg/mL

    缓冲液

    Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2 - 8 °C

    有效期

    12 months
  • 抗原

    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

    别名

    Estrogen Receptor Alpha

    背景

    The estrogen receptor (ER) is the steroid-hormone nuclear receptor that binds estrogen and functions to activate genes involved in a variety of biological processes. Two forms of the ER, ER alpha and ER beta, are encoded by independent genes, and each plays different roles in gene regulation. Additional variants of ER beta have also been reported, these include ERb2, ERb3, ERb4, and ERb5. All forms of the ER have the ability to heterodimerize with each other. Differences in localization and concentrations as well as heterodimerization among the variants may serve to achieve distinct cell and tissue responses. ER alpha generally functions as an activator of transcription while ER beta functions as a repressor.

    基因ID

    2099

    UniProt

    P03372

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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