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ERCC1 抗体

ERCC1 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 2A8 unconjugated
产品编号 ABIN2720404
发货至: 中国
  • 抗原 See all ERCC1 抗体
    ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
    适用
    • 80
    • 38
    • 24
    • 5
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    宿主
    • 55
    • 23
    • 2
    小鼠
    克隆类型
    • 56
    • 24
    单克隆
    标记
    • 52
    • 5
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    • 1
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    This ERCC1 antibody is un-conjugated
    应用范围
    • 73
    • 44
    • 15
    • 13
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    • 10
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    • 7
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    • 2
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    产品特性
    Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1), transcript variant 2
    纯化方法
    Purified from mouse ascites fluids by affinity chromatography
    免疫原
    Full length human recombinant protein of human ERCC1(NP_001974) produced in HEK293T cell.
    克隆位点
    2A8
    亚型
    IgG1
    Top Product
    Discover our top product ERCC1 Primary Antibody
  • 应用备注
    WB 1:500~2000, IF 1:100, FLOW 1:100,
    说明

    The concentration of the product may vary between diferrent lots.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5-1.0 mg/mL
    缓冲液
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
    别名
    ERCC1 (ERCC1 产品)
    别名
    COFS4 antibody, RAD10 antibody, UV20 antibody, Ercc-1 antibody, ercc1 antibody, T12H1.18 antibody, T12H1_18 antibody, UV REPAIR DEFICIENT 7 antibody, UVR7 antibody, ERCC excision repair 1, endonuclease non-catalytic subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 1 antibody, DNA excision repair protein ERCC-1 antibody, nucleotide repair protein antibody, excision repair cross-complementation group 1 L homeolog antibody, excision repair cross-complementation group 1 antibody, ERCC1 antibody, Ercc1 antibody, CC1G_04546 antibody, CpipJ_CPIJ013903 antibody, PITG_13719 antibody, ercc1 antibody, ercc1.L antibody
    背景
    The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.
    分子量
    32.4 kDa
    基因ID
    2067
    NCBI登录号
    NM_001983
    HGNC
    2067
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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