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COL3A1 抗体 (Chain alpha 1)

COL3A1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272016
发货至: 中国
  • 抗原 See all COL3A1 抗体
    COL3A1 (Collagen, Type III, alpha 1 (COL3A1))
    抗原表位
    • 11
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Chain alpha 1
    适用
    • 59
    • 19
    • 18
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 67
    • 11
    • 2
    克隆类型
    • 67
    • 13
    多克隆
    标记
    • 51
    • 11
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COL3A1 antibody is un-conjugated
    应用范围
    • 57
    • 32
    • 18
    • 17
    • 12
    • 12
    • 12
    • 10
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of Collagen III protein (COL3A1).
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product COL3A1 Primary Antibody
  • 应用备注
    ELISA: 1/10000approx. 1/20000. Immunoflourescence: 1/50approx. 1/200. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Xie, Dolder, Siegrist, Wetterwald, Hofstetter: "Glutamate Receptor Agonists and Glutamate Transporter Antagonists Regulate Differentiation of Osteoblast Lineage Cells." in: Calcified tissue international, Vol. 99, Issue 2, pp. 142-54, (2018) (PubMed).

    Schminke, Frese, Bode, Goldring, Miosge: "Laminins and Nidogens in the Pericellular Matrix of Chondrocytes: Their Role in Osteoarthritis and Chondrogenic Differentiation." in: The American journal of pathology, Vol. 186, Issue 2, pp. 410-8, (2016) (PubMed).

    Chen, Yang, Huang, Pan, Liu, Qiu: "Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury." in: The Journal of surgical research, Vol. 185, Issue 2, pp. 740-7, (2013) (PubMed).

    Xie, Li, Wang, Zhang, Peng, Yang, Zou, Ge, Chen, Chen: "In vivo delivery of adenoviral vector containing interleukin-17 receptor a reduces cardiac remodeling and improves myocardial function in viral myocarditis leading to dilated cardiomyopathy." in: PLoS ONE, Vol. 8, Issue 8, pp. e72158, (2013) (PubMed).

    Zhang, Shen, Zhang, Wan, Yao, Wu, Wang, Chen, Yan, Jiang: "Induction of thoracic aortic remodeling by endothelial-specific deletion of microRNA-21 in mice." in: PLoS ONE, Vol. 8, Issue 3, pp. e59002, (2013) (PubMed).

  • 抗原
    COL3A1 (Collagen, Type III, alpha 1 (COL3A1))
    Abstract
    COL3A1 产品
    别名
    EDS4A antibody, AW550625 antibody, Col3a-1 antibody, MMS10-W antibody, Ms10w antibody, mKIAA4231 antibody, col3a1 antibody, collagen type III alpha 1 chain antibody, collagen, type III, alpha 1 antibody, collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog antibody, COL3A1 antibody, Col3a1 antibody, col3a1 antibody, col3a1.S antibody
    背景
    Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in the gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations, these mutations alter splicing, often leading to the exclusion of multiple exons.Synonyms: COL3A1
    分子量
    approx. 138 kDa
    基因ID
    1281
    NCBI登录号
    NP_000081
    UniProt
    P02461
    途径
    Autophagy, Growth Factor Binding
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