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VEGFB 抗体

VEGFB 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN271976
发货至: 中国
  • 抗原 See all VEGFB 抗体
    VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
    适用
    • 78
    • 21
    • 21
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 71
    • 13
    • 1
    克隆类型
    • 75
    • 10
    多克隆
    标记
    • 47
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VEGFB antibody is un-conjugated
    应用范围
    • 73
    • 32
    • 30
    • 14
    • 8
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of VEGFB protein. (region surrounding Arg125)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product VEGFB Primary Antibody
  • 应用备注
    ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
    别名
    VEGF-B (VEGFB 产品)
    别名
    VEGFL antibody, VRF antibody, VEGF-B antibody, Vrf antibody, vascular endothelial growth factor B antibody, VEGFB antibody, Vegfb antibody
    背景
    The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF) and vascular endothelial growth factor (VEGF). VEGF is a dimeric glycoprotein with struc- tural homology to PDGF. Several variants of VEGF have been described that arise by alternative mRNA splicing. It has been speculated that VEGF may function as a tumor angiogenesis factor in vivo. Two additional proteins des- ignated VEGF-B and VEGF-C share a significant degree of homology withVEGF. VEGF-B is abundantly expressed in heart and skeletal muscle and is frequently co-expressed with VEGF. VEGF-C binds to and specifically acti- vates Flt-4 and Flk-1. The genes that encode VEGF-B and VEGF-C have been localized to chromosomes 11q13 and 4q34, respectively.Synonyms: VEGF-related factor, VEGFB, VRF, Vascular endothelial growth factor B
    分子量
    approx. 22 kDa
    基因ID
    7423
    NCBI登录号
    NP_003368
    UniProt
    P49765
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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