NCOR1 抗体
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- 抗原 See all NCOR1 抗体
- NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCOR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of NCoR1 protein. (region surrounding His76)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product NCOR1 Primary Antibody
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anti-Nuclear Receptor Co-Repressor 1 (NCOR1) (AA 1-200) antibody
NCOR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 1 (NCOR1) (N-Term) antibodyNCOR1 适用: 人, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 1 (NCOR1) (AA 1-192) antibodyNCOR1 适用: 人 ELISA, WB, IHC 宿主: 小鼠 Monoclonal 7A7A9 unconjugated
anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibodyNCOR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 1 (NCOR1) (AA 484-533) antibodyNCOR1 适用: 人, 小鼠, Cow, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 1 (NCOR1) (AA 16-47), (N-Term) antibodyNCOR1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB2594 unconjugated
anti-Nuclear Receptor Co-Repressor 1 (NCOR1) (N-Term) antibodyNCOR1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 1 (NCOR1) (AA 1770-1947) antibodyNCOR1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 1 (NCOR1) (AA 2341-2440) antibodyNCOR1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Co-Repressor 1 (NCOR1) antibodyNCOR1 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
- 别名
- NCOR1 (NCOR1 产品)
- 别名
- ncor antibody, zgc:56355 antibody, 5730405M06Rik antibody, A230020K14Rik antibody, N-CoR antibody, RIP13 antibody, Rxrip13 antibody, mKIAA1047 antibody, N-CoR1 antibody, TRAC1 antibody, hN-CoR antibody, nuclear receptor corepressor 1 antibody, nuclear receptor co-repressor 1 antibody, nuclear receptor corepressor 1 pseudogene antibody, nuclear receptor corepressor 1 S homeolog antibody, ncor1 antibody, NCOR1 antibody, CpipJ_CPIJ002507 antibody, LOC100343278 antibody, Ncor1 antibody, ncor1.S antibody
- 背景
- Retinoids are metabolites of vitamin A (retinol) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation.Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs), include RARα, RARβ and RARγ, each of which have a high affinity for all-trans retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. Two cofactors that function to repress transcription, designated SMRT and N-CoR, have been shown to associate with the thyroid receptor and RAR in their unliganded state and are released from them upon ligand binding. The carboxy termini of both proteins contain receptor interacting domains while their amino termini contain two previously undescribed repressor domains. SMRT (silencing mediator for RARs and TRs) is 1495 amino acids in length with an estimated molecular weight of 168 kDa. N-CoR (nuclear receptor corepressor) is a protein 2453 amino acids in length with a relative molecular weight of 270 kDa.Synonyms: KIAA1047, N-CoR, N-CoR1, Nuclear receptor corepressor 1
- 分子量
- approx. 270 kDa
- 基因ID
- 9611
- NCBI登录号
- NP_001177369
- UniProt
- O75376
- 途径
- Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
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