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NCOR1 产品

(Nuclear Receptor Co-Repressor 1 (NCOR1))
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010].

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Featured NCOR1 Categories

NCOR1 抗体

High quality antibodies with extensive validation data.

NCOR1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NCOR1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NCOR1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6144420
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6263544
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC
Validations
  • (2)
  • (2)
Cat. No. ABIN969310
Quantity 100 μL
Datasheet Datasheet

Recommended NCOR1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969003
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969002
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969001
Quantity 96 tests
Datasheet Datasheet

Recommended NCOR1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312138
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420504
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420507
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our NCOR1 Products

Tan, Zhang, Li, Mu, Wang, Zhang, Jiang, Li, Yang, Liu, Gao: "Abnormally localized DLK1 interacts with NCOR1 in non-small cell lung cancer cell nuclear." in: Bioscience reports, Vol. 39, Issue 12, (2019) (PubMed).

Nazha, Granner, Maloney, Odashiro, Antecka, Burnier: "Aberrant nuclear repressor coreceptor 1 localization in human retinoblastoma." in: Ophthalmic research, Vol. 49, Issue 4, pp. 171-6, (2013) (PubMed).

Bonofiglio, Santoro, Martello, Vizza, Rovito, Cappello, Barone, Giordano, Panza, Catalano, Iacobazzi, Dolce, Andò: "Mechanisms of divergent effects of activated peroxisome proliferator-activated receptor-γ on mitochondrial citrate carrier expression in 3T3-L1 fibroblasts and mature adipocytes." in: Biochimica et biophysica acta, Vol. 1831, Issue 6, pp. 1027-36, (2013) (PubMed).

Dai, Hussain: "NR2F1 disrupts synergistic activation of the MTTP gene transcription by HNF-4α and HNF-1α." in: Journal of lipid research, Vol. 53, Issue 5, pp. 901-8, (2012) (PubMed).

Alenghat, Meyers, Mullican, Leitner, Adeniji-Adele, Avila, Bu?an, Ahima, Kaestner, Lazar: "Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology." in: Nature, Vol. 456, Issue 7224, pp. 997-1000, (2008) (PubMed).

Atsumi, Tomita, Kiyoi, Naoe: "Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo." in: Biochemical and biophysical research communications, Vol. 345, Issue 4, pp. 1471-80, (2006) (PubMed).

Zhang, Yoon, Wong: "JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)." in: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6404-14, (2005) (PubMed).

Ishizuka, Lazar: "The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor." in: Molecular and cellular biology, Vol. 23, Issue 15, pp. 5122-31, (2003) (PubMed).

Tai, Geisterfer, Bell, Moniwa, Davie, Boucher, McBurney: "CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins." in: Biochemical and biophysical research communications, Vol. 308, Issue 1, pp. 170-6, (2003) (PubMed).

Loinder, Söderström: "The nuclear receptor corepressor (N-CoR) modulates basal and activated transcription of genes controlled by retinoic acid." in: The Journal of steroid biochemistry and molecular biology, Vol. 84, Issue 1, pp. 15-21, (2003) (PubMed).

Synonyms and alternative names related to NCOR1

nuclear receptor corepressor 1 (ncor1), nuclear receptor corepressor 1 (NCOR1), nuclear receptor co-repressor 1 (CpipJ_CPIJ002507), nuclear receptor corepressor 1 pseudogene (LOC100343278), nuclear receptor co-repressor 1 (Ncor1), nuclear receptor corepressor 1 S homeolog (ncor1.S), 5730405M06Rik, A230020K14Rik, hN-CoR, mKIAA1047, N-CoR, N-CoR1, ncor, RIP13, Rxrip13, TRAC1, zgc:56355

Protein level used designations for NCOR1

  • nuclear receptor corepressor 1
  • nuclear receptor co-repressor 1
  • N-CoR1
  • retinoid X receptor interacting protein 13
  • retinoid X receptor-interacting protein 13
  • N-CoR
  • N-Cor/SMRT corepressor Rip13
  • N-Cor/SMRT corepressor, Rip13
  • NCoR
  • thyroid hormone- and retinoic acid receptor-associated corepressor 1
  • xN-CoR
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