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STAT4 抗体

STAT4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN271914
发货至: 中国
  • 抗原 See all STAT4 抗体
    STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
    适用
    • 81
    • 52
    • 34
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 89
    • 6
    • 2
    • 2
    克隆类型
    • 86
    • 13
    多克隆
    标记
    • 50
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STAT4 antibody is un-conjugated
    应用范围
    • 75
    • 47
    • 39
    • 21
    • 21
    • 15
    • 13
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    STAT4 (E687) antibody detects endogenous levels of STAT4 protein.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product STAT4 Primary Antibody
  • 应用备注
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
    别名
    STAT4 (STAT4 产品)
    别名
    SLEB11 antibody, signal transducer and activator of transcription 4 antibody, STAT4 antibody, stat4 antibody, Stat4 antibody
    背景
    Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expresion of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.Synonyms: Signal transducer and activator of transcription 4
    分子量
    approx. 88 kDa
    基因ID
    6775
    NCBI登录号
    NP_003142
    UniProt
    Q14765
    途径
    JAK/STAT Signaling
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