STAT4 抗体 (N-Term)
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北京 101111
Quick Overview for STAT4 抗体 (N-Term) (ABIN2777897)
抗原
See all STAT4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- STAT4 Antibody - N-terminal region
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序列
- IGGPLHNGLD QLQNCFTLLA ESLFQLRRQL EKLEEQSTKM TYEGDPIPMQ
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预测反应
- Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against STAT4. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human STAT4
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111738
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26789-96, (2004) (PubMed).
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- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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别名
- STAT4
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背景
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Background Information: STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.
Gene Name: Signal transducer and activator of transcription 4
Alternative Symbols: SLEB11
Protein Name: Signal transducer and activator of transcription 4
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分子量
- 86 kDa
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基因ID
- 6775
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NCBI登录号
- NP_003142
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UniProt
- Q14765
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途径
- JAK/STAT Signaling
抗原
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