KAT2B 抗体
Quick Overview for KAT2B 抗体 (ABIN271904)
抗原
See all KAT2B 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of PCAF protein. (region surrounding Phe820)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibody
KAT2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5E5 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibodyKAT2B 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 1-142) antibodyKAT2B 适用: 人, 小鼠, 大鼠, 猴 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7D12C8 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 451-550) antibodyKAT2B 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (C-Term) antibodyKAT2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibodyKAT2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B4 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (C-Term) antibodyKAT2B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (acLys428) antibodyKAT2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (acLys428) antibodyKAT2B 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 583-832) antibodyKAT2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
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别名
- PCAF / KAT2B
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背景
- In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAFII p250. Mammalian HDAC1 (also designated HD1) and HDAC2 (also designated mammalian RPD3), both of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.Synonyms: Histone acetylase PCAF, Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Lysine acetyltransferase 2B, P/CAF, P300/CBP-associated factor
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分子量
- approx. 93 kDa
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基因ID
- 8850
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NCBI登录号
- NP_003875
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UniProt
- Q92831
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途径
- p53 Pathway, Regulation of Carbohydrate Metabolic Process
抗原
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