VAV1 抗体
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- 抗原 See all VAV1 抗体
- VAV1 (Vav 1 Oncogene (VAV1))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VAV1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of VAV1 protein. (region surrounding Ala168)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product VAV1 Primary Antibody
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anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody
VAV1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2-00E-11 unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 565-795) antibodyVAV1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (pTyr174) antibodyVAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 681-790) antibodyVAV1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 9C1 unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 681-790) antibodyVAV1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-Vav 1 Oncogene (VAV1) (N-Term) antibodyVAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (Center) antibodyVAV1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (Tyr174) antibodyVAV1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 100-200) antibodyVAV1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 1 Oncogene (VAV1) (AA 426-696) antibodyVAV1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/5000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- VAV1 (Vav 1 Oncogene (VAV1))
- 别名
- VAV1 (VAV1 产品)
- 别名
- VAV antibody, Vav antibody, vav-T antibody, vav guanine nucleotide exchange factor 1 antibody, vav 1 oncogene antibody, vav guanine nucleotide exchange factor 1 L homeolog antibody, VAV1 antibody, Vav1 antibody, vav1.L antibody
- 背景
- The Vav gene was originally identified on the basis of its oncogenic activation during the course of gene transfer assays. The major translational product of the Vav proto-oncogene has been identified as a protein containing an array of structural motifs. Contained within its amino terminus are a helix-loop-helix domain and a leucine zipper motif similar to that of Myc family proteins, deletion of this region of p95Vav causes its oncogenic activation. In addition, p95Vav contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of p95Vav is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages. These results suggest that p95Vav may represent a new type of signal transduction molecule involved in the transduction of tyrosine phosphorylation signaling into transcriptional events.Synonyms: Proto-oncogene vav, VAV-1
- 分子量
- approx. 100 kDa
- 基因ID
- 7409
- NCBI登录号
- NP_005419
- UniProt
- P15498
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
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