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VAV1 抗体 (AA 100-200)

VAV1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7271302
发货至: 中国
  • 抗原 See all VAV1 抗体
    VAV1 (Vav 1 Oncogene (VAV1))
    抗原表位
    • 15
    • 11
    • 10
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-200
    适用
    • 69
    • 39
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 67
    • 4
    克隆类型
    • 67
    • 4
    多克隆
    标记
    • 40
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    This VAV1 antibody is un-conjugated
    应用范围
    • 46
    • 34
    • 12
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    VAV1 Rabbit pAb
    序列
    FDVQDFGKVI YTLSALSWTP IAQNRGIMPF PTEEESVGDE DIYSGLSDQI DDTVEEDEDL YDCVENEEAE GDEIYEDLMR SEPVSMPPKM TEYDKRCCCL R
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 100-200 of human VAV1 (NP_005419.2).
    亚型
    IgG
    Top Product
    Discover our top product VAV1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    VAV1 (Vav 1 Oncogene (VAV1))
    别名
    VAV1 (VAV1 产品)
    别名
    VAV antibody, Vav antibody, vav-T antibody, vav guanine nucleotide exchange factor 1 antibody, vav 1 oncogene antibody, vav guanine nucleotide exchange factor 1 L homeolog antibody, VAV1 antibody, Vav1 antibody, vav1.L antibody
    背景
    This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,VAV1,VAV,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,G protein signaling,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Cytoskeleton,Actins,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,VAV1
    分子量
    94kDa/98kDa
    基因ID
    7409
    UniProt
    P15498
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
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