PKC zeta 抗体
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Quick Overview for PKC zeta 抗体 (ABIN271785)
抗原
See all PKC zeta (PRKCZ) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of PKC ζ protein. (region surrounding Pro404)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Protein Kinase C, zeta (PRKCZ) (pThr410) antibody
PRKCZ 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (C-Term) antibodyPRKCZ 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (AA 165-255) antibodyPRKCZ 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (AA 453-592) antibodyPRKCZ 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (Cytoplasmic Domain) antibodyPRKCZ 适用: 人 IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (pThr560) antibodyPRKCZ 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) antibodyPRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Monoclonal R14-K unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (AA 166-197), (N-Term) antibodyPRKCZ 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01027 unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (AA 1-592) antibodyPRKCZ 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (N-Term) antibodyPRKCZ 适用: 人 IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
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别名
- PRKCZ
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背景
- Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (α, βI, Βii and γ) and novel (n) PKC isoforms (δ, ε , ζ, η and θ). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC δ and ε are independent of Ca++. On the other hand, nPKC δ and ε, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activitiesSynonyms: PKC zeta, PKC-zeta, PKC2, Protein kinase C zeta type, nPKC-zeta
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分子量
- approx. 70 to 85 kDa
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基因ID
- 5590
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NCBI登录号
- NP_001028753
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UniProt
- Q05513
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途径
- NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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