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Integrin beta 7 抗体

ITGB7 适用: 人 FACS 宿主: 大鼠 Monoclonal FIB504 unconjugated
产品编号 ABIN2689794
发货至: 中国
  • 抗原 See all Integrin beta 7 (ITGB7) 抗体
    Integrin beta 7 (ITGB7)
    适用
    • 62
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    宿主
    • 47
    • 7
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    大鼠
    克隆类型
    • 51
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    • 2
    单克隆
    标记
    • 30
    • 7
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    This Integrin beta 7 antibody is un-conjugated
    应用范围
    • 44
    • 27
    • 14
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    • 13
    • 6
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    • 4
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    • 4
    • 3
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    产品特性
    FIB504 reacts with mouse integrin β7 subunit (130 kD) but also cross reacts with human integrin β7. Integrin β7 associates with α4 (CD49d) expressed on subsets of lymphocytes and thymus. It also associates with αIEL (CD103) expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Integrin β7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. Profile of peripheral blood lymphocytes analyzed on a FACScan

    BD Pharmingen™ Purified Rat Anti-Human Integrin β7 - Purified - Clone FIB504 - Isotype Rat IgG2a, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    FIB504
    亚型
    IgG2a kappa
    Top Product
    Discover our top product ITGB7 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Butcher, Picker: "Lymphocyte homing and homeostasis." in: Science (New York, N.Y.), Vol. 272, Issue 5258, pp. 60-6, (1996) (PubMed).

    Teague, Lazarovits, McIntyre: "Integrin alpha 4 beta 7 co-stimulation of human peripheral blood T cell proliferation." in: Cell adhesion and communication, Vol. 2, Issue 6, pp. 539-47, (1995) (PubMed).

    Erle, Briskin, Butcher, Garcia-Pardo, Lazarovits, Tidswell: "Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 2, pp. 517-28, (1994) (PubMed).

    Berlin, Berg, Briskin, Andrew, Kilshaw, Holzmann, Weissman, Hamann, Butcher: "Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1." in: Cell, Vol. 74, Issue 1, pp. 185-95, (1993) (PubMed).

  • 抗原
    Integrin beta 7 (ITGB7)
    别名
    Integrin Beta7 (ITGB7 产品)
    别名
    Ly69 antibody, integrin beta 7 antibody, integrin subunit beta 7 antibody, integrin, beta 7 antibody, Itgb7 antibody, ITGB7 antibody
    途径
    Integrin Complex
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