(2 references)-
- 抗原 See all IL-21 (IL21) 抗体
- IL-21 (IL21) (Interleukin 21 (IL21))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL-21 antibody is conjugated to Biotin
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应用范围
- ELISA
- 品牌
- BD Pharmingen™
- 产品特性
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The I76-539 antibody reacts with interleukin-21 (IL-21), an ~ 15 kDa member of the type-I-cytokine family of proteins. IL-21 is expressed primarily by CD4+ T cells and has a broad range of immunoregulatory functions on B cells, CD8+ T cells, NK cells and dendritic cells. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of T cells and augmentation of antitumor activity of CD8+ T cells. It has been speculated that IL-21, through its varies positive and negative regulatory effects on cell-mediated and humoral immunity, may play a role in autoimmuninty, allergy, asthma and tumor regression. Human IL-21 sandwich ELISA curve: The curve was generated by a sandwich ELISA using the purified J148-1134 as capture antibody(Cat. No. 558503), doubling dilutions of recombinant human IL-21 protein and biotin I76-539 as detection antibody. Streptavidin-HRP (Cat. No. 554066) plus TMB substrate (Cat. No. 555214)were used to develop the ELISA.
BD Pharmingen™ Biotin Mouse anti-Human IL-21 - Biotin - Clone I76-539 - Isotype Mouse IgG1, κ - 0.5 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human IL-21
- 克隆位点
- I76
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product IL21 Primary Antibody
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anti-Interleukin 21 (IL21) (AA 25-162) antibody
IL21 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 1-162) antibodyIL21 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 65-155) antibodyIL21 适用: 人, 小鼠 WB, ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 25-146) antibodyIL21 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 25-162) antibodyIL21 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 23-155) antibodyIL21 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) antibodyIL21 适用: 人, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 1-146) antibodyIL21 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 21 (IL21) (AA 63-162) antibodyIL21 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation." in: Nature reviews. Immunology, Vol. 5, Issue 9, pp. 688-98, (2005) (PubMed).
: "Interleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses." in: Immunology, Vol. 112, Issue 2, pp. 177-82, (2004) (PubMed).
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: "Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation." in: Nature reviews. Immunology, Vol. 5, Issue 9, pp. 688-98, (2005) (PubMed).
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- 抗原
- IL-21 (IL21) (Interleukin 21 (IL21))
- 别名
- IL-21 (IL21 产品)
- 别名
- IL-21 antibody, Za11 antibody, interleukin 21 antibody, IL21 antibody, Il21 antibody
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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