(3 references)-
- 抗原 See all FCGR1A 抗体
- FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FCGR1A antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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The monoclonal antibody 10.1 reacts with CD64, a 75 kD type I transmembrane glycoprotein that is a high affinity receptor for IgG (FcγRI). CD64, a key receptor in the development of immune responses, has a dual role as a low affinity receptor for IgG3 and high affinity receptor for IgG2a linking innate and adaptive immunities. CD64 mediates endocytosis, phagocytosis, antibody-dependent cellular toxicity, cytokine release and superoxide generation. CD64 is expressed largely on macrophages and dendritic cells. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood monocytes analyzed on a FACScan
BD Pharmingen™ Biotin Mouse Anti-Human CD64 - Biotin - Clone 10.1 - Isotype Mouse IgG1, κ - Reactivity Hu - 100 Tests - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- 10-1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FCGR1A Primary Antibody
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anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 200-292) antibody
FCGR1A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-145) antibodyFCGR1A 适用: 人 FACS, WB, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 5F5F12 unconjugated
anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) antibodyFCGR1A 适用: 人, Non-Human Primate FACS, WB, ICC, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 10-1 unconjugated
anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) antibodyFCGR1A 适用: 人, Non-Human Primate FACS, WB, ICC, IP, IHC (p), Func, IHC (fro) 宿主: 小鼠 Monoclonal 10-1 unconjugated
anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) antibody (FITC)FCGR1A 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal 10-1 FITC
anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) antibody (APC)FCGR1A 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal 10-1 APC
anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 230-280) antibodyFCGR1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 35-235) antibodyFCGR1A 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-115) antibodyFCGR1A 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (Internal Region) antibodyFCGR1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 样本量
- 20 μL
- 限制
- 仅限研究用
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- 缓冲液
- Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "The high affinity Fc gamma receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: the gamma subunit of Fc gamma RIIIA imparts phagocytic function to Fc gamma RI." in: Experimental hematology, Vol. 22, Issue 7, pp. 599-606, (1994) (PubMed).
: "The human mononuclear phagocyte high-affinity Fc receptor, FcRI, defined by a monoclonal antibody, 10.1." in: European journal of immunology, Vol. 17, Issue 10, pp. 1453-9, (1987) (PubMed).
: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).
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: "The high affinity Fc gamma receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: the gamma subunit of Fc gamma RIIIA imparts phagocytic function to Fc gamma RI." in: Experimental hematology, Vol. 22, Issue 7, pp. 599-606, (1994) (PubMed).
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- 抗原
- FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
- 别名
- CD64 (FCGR1A 产品)
- 别名
- CD64 antibody, CD64A antibody, FCRI antibody, IGFR1 antibody, FcgammaRI antibody, Fcgr1 antibody, Fcgr1b antibody, AI323638 antibody, AV092959 antibody, IGGHAFC antibody, FCGR1A antibody, Fc fragment of IgG receptor Ia antibody, Fc receptor, IgG, high affinity I antibody, FCGR1A antibody, Fcgr1a antibody, Fcgr1 antibody
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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