Prostaglandin D2 Receptor 2 (PTGDR2) 抗体
(3 references)-
- 抗原 See all Prostaglandin D2 Receptor 2 (PTGDR2) 抗体
- Prostaglandin D2 Receptor 2 (PTGDR2)
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适用
- 人
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Monoclonal antibody BM16 reacts with CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells). CRTH2 is a member of the G protein-coupled leukocyte chemoattractant receptor family and it is expressed on Th2, but not Th1 lineage cells. It is detectable on CD4+ T cells in fresh PBMC and no significant expression on B cells and NK cells. CRTH2 is also expressed on peripheral blood basophils and eosinophils, suggesting its involvement allergic reactions. Phenotypic analysis of CD4+ T cells expressing CRTH2 demonstrated CD45RA-, CD45RO+ and CD25+. These cells produce Th2- but little or no Th1-type cytokines upon stimulation with PMA and Ionomycin. Profile of anti-CRTH2 (BM16) reactivity on HUT 78 cells analyzed by flow cytometry. Second step staining with Cat. No. 554016.
BD Pharmingen™ Purified Rat Anti-Human CD294 - Purified - Clone BM16 - Isotype Rat IgG2a, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Transfectant cells
- 克隆位点
- BM16
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product PTGDR2 Primary Antibody
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anti-Prostaglandin D2 Receptor 2 (PTGDR2) (Extracellular Domain) antibody
PTGDR2 适用: 人, 猴 IHC (p), IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) antibody (APC)PTGDR2 适用: 人 FACS 宿主: 大鼠 Monoclonal BM16 APC
anti-Prostaglandin D2 Receptor 2 (PTGDR2) antibody (PE)PTGDR2 适用: 人 FACS 宿主: 大鼠 Monoclonal BM16 PE
anti-Prostaglandin D2 Receptor 2 (PTGDR2) (N-Term) antibodyPTGDR2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) (3rd Extracellular Loop), (AA 270-283) antibodyPTGDR2 适用: 小鼠, 大鼠 WB, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) (Extracellular Domain) antibodyPTGDR2 适用: 人, 猴 IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) antibodyPTGDR2 适用: 人 FACS 宿主: 大鼠 Monoclonal BM16 unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) (Extracellular Domain) antibodyPTGDR2 适用: 人, Gorilla IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) (3rd Extracellular Domain) antibodyPTGDR2 适用: 人, 猴, Gorilla IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) (2nd Extracellular Domain) antibodyPTGDR2 适用: 人, 猴 IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease." in: European journal of immunology, Vol. 30, Issue 10, pp. 2972-9, (2000) (PubMed).
: "CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s)." in: FEBS letters, Vol. 459, Issue 2, pp. 195-9, (1999) (PubMed).
: "Selective expression of a novel surface molecule by human Th2 cells in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 3, pp. 1278-86, (1999) (PubMed).
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: "CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease." in: European journal of immunology, Vol. 30, Issue 10, pp. 2972-9, (2000) (PubMed).
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- 抗原
- Prostaglandin D2 Receptor 2 (PTGDR2)
- 别名
- CD294 (PTGDR2 产品)
- 别名
- CD294 antibody, CRTH2 antibody, DL1R antibody, DP2 antibody, GPR44 antibody, Crth2 antibody, Grp45 antibody, Ptgdr2 antibody, Gpr44 antibody, prostaglandin D2 receptor 2 antibody, PTGDR2 antibody, Ptgdr2 antibody
- 背景
- Synonyms: CRTH2
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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