(1 reference)-
- 抗原 See all CD226 抗体
- CD226
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CD226 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
-
The DX11 monoclonal antibody specifically binds to CD226 which is also known as DNAX accessory molecule-1 (DNAM-1), Platelet and T cell activation antigen 1 (PTA1), or T lineage-specific activation antigen 1 antigen (TLiSA1). CD226 is a 65 kDa type 1 transmembrane glycoprotein consisting of 318 amino acid residues including two Ig-like domains. CD226 is expressed on the majority of T cells, NK cells, monocytes, platelets, and a subset of B cells, but not on granulocytes or erythrocytes. It is also present on a subset of thymocytes coexpressing high density surface CD3. CD226 is not present on normal fibroblast cell lines or tumor cell lines of epithelial or neuronal origins. CD226 is a tyrosine phosphorylated, signal-transducing molecule which participates in primary adhesion during cytotoxic T lymphocyte (CTL)- or NK cell-mediated cytotoxicity. The DX11 antibody inhibits T- and NK cell-mediated cytotoxicity against a variety of tumor cell targets, and blocks cytokine production by alloantigen-specific T cells. Profile of peripheral blood lymphocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.
BD Pharmingen™ Purified Mouse Anti-Human CD226 - Purified - Clone DX11 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- DX11
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD226 Primary Antibody
-
anti-CD226 (CD226) (AA 19-254) antibody
CD226 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (AA 19-247) antibodyCD226 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM95 unconjugated
anti-CD226 (CD226) (Tyr570) antibodyCD226 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (AA 19-254) antibodyCD226 适用: 人 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 5E3A8 unconjugated
anti-CD226 (CD226) antibodyCD226 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (Ser329) antibodyCD226 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (AA 102-251) antibodyCD226 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (C-Term) antibodyCD226 适用: 人, 小鼠, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (AA 287-336), (pSer329) antibodyCD226 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) antibodyCD226 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
-
-
: "DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes." in: Immunity, Vol. 4, Issue 6, pp. 573-81, (1996) (PubMed).
-
: "DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes." in: Immunity, Vol. 4, Issue 6, pp. 573-81, (1996) (PubMed).
-
- 抗原
- CD226
- 别名
- CD226 (CD226 产品)
- 别名
- CD226 antibody, cd226 antibody, zgc:158817 antibody, BC051526 antibody, DNAM-1 antibody, DNAM1 antibody, Pta1 antibody, TLiSA1 antibody, PTA1 antibody, CD226 molecule antibody, CD226 antigen antibody, CD226 antibody, cd226 antibody, Cd226 antibody
- 背景
- Synonyms: DNAM-1, DNAM1, PTA1, PTA-1, TLiSA1
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
-
You are here:
