(4 references)-
- 抗原 See all KIR2DL3 抗体
- KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KIR2DL3 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with a 50 - 58 kDa type I glycoprotein molecule of the killer cell inhibitory receptor (KIR) family of proteins. CD158b has also been known as GLI83, p50.2, or p58.2. CD158b is composed of two extracellular Ig-like domains. It is expressed on a subset of NK cells and it may also be present on rare T cells (either CD3/TCR αβ+, or CD3/TCR γδ+). CD158b regulates NK cell mediated cytolytic activity by interacting with HLA-C alleles (Cw 1, 3, 7 and 8). This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD158b - Purified - Clone CH-L - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- CH
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product KIR2DL3 Primary Antibody
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anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 42-140) antibody
KIR2DL3 适用: 人 ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (Internal Region) antibodyKIR2DL3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-245) antibodyKIR2DL3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) antibodyKIR2DL3 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-245) antibodyKIR2DL3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-342) antibodyKIR2DL3 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) antibodyKIR2DL3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 190IIC311 unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 1-341) antibodyKIR2DL3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) antibodyKIR2DL3 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Molecular basis of HLA-C recognition by p58 natural killer cell inhibitory receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 8, pp. 3875-82, (1997) (PubMed).
: "The natural killer-related receptor for HLA-C expressed on T cells from CD3+ lymphoproliferative disease of granular lymphocytes displays either inhibitory or stimulatory function." in: Blood, Vol. 87, Issue 6, pp. 2369-75, (1996) (PubMed).
: "Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells." in: Science (New York, N.Y.), Vol. 268, Issue 5209, pp. 405-8, (1995) (PubMed).
: "T cell clones expressing the natural killer cell-related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function." in: European journal of immunology, Vol. 24, Issue 10, pp. 2294-8, (1994) (PubMed).
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: "Molecular basis of HLA-C recognition by p58 natural killer cell inhibitory receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 8, pp. 3875-82, (1997) (PubMed).
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- 抗原
- KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
- 别名
- CD158b (KIR2DL3 产品)
- 别名
- CD158B2 antibody, CD158b antibody, GL183 antibody, KIR-023GB antibody, KIR-K7b antibody, KIR-K7c antibody, KIRCL23 antibody, NKAT antibody, NKAT2 antibody, NKAT2A antibody, NKAT2B antibody, p58 antibody, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 antibody, KIR2DL3 antibody
- 途径
- Cancer Immune Checkpoints
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