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TNFSF9 抗体

TNFSF9 适用: 人 FACS 宿主: 小鼠 Monoclonal C65 unconjugated
产品编号 ABIN2688965
发货至: 中国
  • 抗原 See all TNFSF9 抗体
    TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
    适用
    • 57
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    宿主
    • 42
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TNFSF9 antibody is un-conjugated
    应用范围
    • 48
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    产品特性
    Reacts with a type II membrane protein known as 4-1BB ligand. This molecule belongs to the TNF superfamily. It has been reported to have costimulatory function on activated T cells. Reports suggest that stimulation of activated T cells via 4-1BB ligand does not require the presence of other costimulatory molecules, including CD28. Some studies have reported human 4-1BB ligand to be expressed preferentially on primary B cells and B-cell lines. C65-485 antibody is able to react with recombinant human 4-1BB ligand (rh4-1BBL) bound to CD137 (4-1BB receptor) expressed on PHA-stimulated PBMC. Profile of Hut-78 cell line analzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD137 Ligand - Purified - Clone C65-485 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    C65
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TNFSF9 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Melero, Bach, Hellström, Aruffo, Mittler, Chen: "Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway." in: European journal of immunology, Vol. 28, Issue 3, pp. 1116-21, (1998) (PubMed).

    Chu, DeBenedette, Stiernholm, Barber, Watts: "Role of IL-12 and 4-1BB ligand in cytokine production by CD28+ and CD28- T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 7, pp. 3081-9, (1997) (PubMed).

    DeBenedette, Shahinian, Mak, Watts: "Costimulation of CD28- T lymphocytes by 4-1BB ligand." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 2, pp. 551-9, (1997) (PubMed).

    Zhou, Kim, Hurtado, Lee, Kim, Pollok, Kwon: "Characterization of human homologue of 4-1BB and its ligand." in: Immunology letters, Vol. 45, Issue 1-2, pp. 67-73, (1995) (PubMed).

  • 抗原
    TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
    别名
    CD137 Ligand (TNFSF9 产品)
    别名
    TNFSF9 antibody, 4-1BB-L antibody, 4-1BBL antibody, AI848817 antibody, Cd137l antibody, Ly63l antibody, CD137L antibody, TNF superfamily member 9 antibody, tumor necrosis factor (ligand) superfamily, member 9 antibody, Tnfsf9 antibody, LOC476729 antibody, TNFSF9 antibody
    背景
    Synonyms: 4-1BB Ligand
    途径
    Activated T Cell Proliferation, Cancer Immune Checkpoints
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