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- 抗原 See all TNFSF9 抗体
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFSF9 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with a type II membrane protein known as 4-1BB ligand. This molecule belongs to the TNF superfamily. It has been reported to have costimulatory function on activated T cells. Reports suggest that stimulation of activated T cells via 4-1BB ligand does not require the presence of other costimulatory molecules, including CD28. Some studies have reported human 4-1BB ligand to be expressed preferentially on primary B cells and B-cell lines. C65-485 antibody is able to react with recombinant human 4-1BB ligand (rh4-1BBL) bound to CD137 (4-1BB receptor) expressed on PHA-stimulated PBMC. Profile of Hut-78 cell line analzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD137 Ligand - Purified - Clone C65-485 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- C65
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TNFSF9 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway." in: European journal of immunology, Vol. 28, Issue 3, pp. 1116-21, (1998) (PubMed).
: "Role of IL-12 and 4-1BB ligand in cytokine production by CD28+ and CD28- T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 7, pp. 3081-9, (1997) (PubMed).
: "Costimulation of CD28- T lymphocytes by 4-1BB ligand." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 2, pp. 551-9, (1997) (PubMed).
: "Characterization of human homologue of 4-1BB and its ligand." in: Immunology letters, Vol. 45, Issue 1-2, pp. 67-73, (1995) (PubMed).
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Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway." in: European journal of immunology, Vol. 28, Issue 3, pp. 1116-21, (1998) (PubMed).
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- 抗原
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
- 别名
- CD137 Ligand (TNFSF9 产品)
- 别名
- TNFSF9 antibody, 4-1BB-L antibody, 4-1BBL antibody, AI848817 antibody, Cd137l antibody, Ly63l antibody, CD137L antibody, TNF superfamily member 9 antibody, tumor necrosis factor (ligand) superfamily, member 9 antibody, Tnfsf9 antibody, LOC476729 antibody, TNFSF9 antibody
- 背景
- Synonyms: 4-1BB Ligand
- 途径
- Activated T Cell Proliferation, Cancer Immune Checkpoints
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