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CD11c 抗体

ITGAX 适用: 小鼠 FACS, IHC (p), IHC (fro), IHC (f), IHC (zinc) 宿主: Armenian Hamster Monoclonal HL3 unconjugated
产品编号 ABIN2688920
发货至: 中国
  • 抗原 See all CD11c (ITGAX) 抗体
    CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
    适用
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    小鼠
    宿主
    • 115
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    Armenian Hamster
    克隆类型
    • 155
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    单克隆
    标记
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    This CD11c antibody is un-conjugated
    应用范围
    • 124
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    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc))
    品牌
    BD Pharmingen™
    产品特性
    The HL3 monoclonal antibody specifically binds to the integrin αx chain of gp150, 95 (CD11c/CD18) which is expressed on dendritic cells and CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and is upregulated on IEL and lymph-node T cells following in vivo activation. CD11c is also found on human NK cells. Although its expression on mouse NK cells is not published, we have detected CD11c on mouse splenic NK cells. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. CD11c plays a role in binding of iC3b. Expression of CD11c on spleen dendritic cells. The frozen section of normal mouse spleen was stained with HL3 mAb. Note the brown labeling of irregular-shaped cells in the red pulp surrounding lymphoid follicles.

    BD Pharmingen™ Purified Hamster Anti-Mouse CD11c - Purified - Clone HL3 - Isotype Armenian Hamster IgG1, λ2 - Reactivity Ms - 1 mL
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
    克隆位点
    HL3
    亚型
    IgG1 lambda
    Top Product
    Discover our top product ITGAX Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    125 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Fagarasan, Muramatsu, Suzuki, Nagaoka, Hiai, Honjo: "Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora." in: Science (New York, N.Y.), Vol. 298, Issue 5597, pp. 1424-7, (2002) (PubMed).

    Huleatt, Lefrançois: "Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 11, pp. 5684-93, (1995) (PubMed).

    Larson, Springer: "Structure and function of leukocyte integrins." in: Immunological reviews, Vol. 114, pp. 181-217, (1990) (PubMed).

  • 抗原
    CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
    别名
    CD11c (ITGAX 产品)
    别名
    CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
    背景
    Synonyms: Cd11c, Itgax, Integrin alpha-X, Integrin αX, Cr4, Complement receptor 4
    途径
    Complement System, Activated T Cell Proliferation, Integrin Complex
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