Endoglin 抗体
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- 抗原 See all Endoglin (ENG) 抗体
- Endoglin (ENG)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Endoglin antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc))
- 品牌
- BD Pharmingen™
- 产品特性
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The 266 monoclonal antibody specifically binds to CD105. CD105 presents an integral membrane homodimer protein with subunits of 95 kDa found on vascular endothelial cells and syncytiotrophoblasts of placenta. CD105 is weakly expressed on stromal fibroblasts. It is also expressed on U937 cells, activated macrophages, and mesenchymal stem cells. CD105 is a component of the TGF-β receptor system in human umbilical vein endothelial cells and binds TGF-β1 and TGF-β3 with high affinity but does not bind toTGF-β2. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation.
BD Pharmingen™ Purified Mouse Anti-Human CD105 - Purified - Clone 266 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human Umbilical Vein Endothelial Cells
- 克隆位点
- 266
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ENG Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen." in: European journal of immunology, Vol. 22, Issue 2, pp. 393-7, (1992) (PubMed).
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Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen." in: European journal of immunology, Vol. 22, Issue 2, pp. 393-7, (1992) (PubMed).
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- 抗原
- Endoglin (ENG)
- 别名
- CD105 (ENG 产品)
- 别名
- ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody
- 背景
- Synonyms: Endoglin, ENG, END, HHT1, ORW, ORW1
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