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BAFF 抗体

TNFSF13B 适用: 人 ELISA 宿主: 小鼠 Monoclonal H32 unconjugated
产品编号 ABIN2688855
发货至: 中国
  • 抗原 See all BAFF (TNFSF13B) 抗体
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This BAFF antibody is un-conjugated
    应用范围
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    ELISA
    品牌
    BD Pharmingen™
    产品特性
    Antibody H32-406 reacts with B-lymphocyte stimulator protein (Blys), also known as BAFF (B cell activating factor) and is a member of the TNF ligand superfamily. Members of the TNF receptor and ligand superfamily play a critical role in regulating immune responses. Blys is a type II membrane protein expressed on cells of myeloid lineage including monocytes, dendritic cells, and activated T cells. Blys exists in both a membrane-bound and soluble form. In its soluble form, Blys is a potent B cell growth factor in costimulation assays, suggesting its biological role in monocyte-driven B cell activation. Blys has also been linked to B cell hyperplasia and autoimmunity. Human Blys sandwich ELISA curve: The curve was generated by a sandwich ELISA using the purified H32-406 as capture antibody, doubling dilutions of recombinant human Blys protein and biotin H32-544 (Cat. No. 558290) as detection antibody. Streptavidin-HRP (Cat. No. 554066) plus TMB substrate (Cat. No. 555214)were used to develop the ELISA.

    BD Pharmingen™ Purified Mouse anti-Human Blys (BAFF) - Purified - Clone H32-406 - Isotype Mouse IgG1, κ - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    H32
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TNFSF13B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Craxton, Magaletti, Ryan, Clark: "Macrophage- and dendritic cell--dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF." in: Blood, Vol. 101, Issue 11, pp. 4464-71, (2003) (PubMed).

    Mackay, Schneider, Rennert, Browning: "BAFF AND APRIL: a tutorial on B cell survival." in: Annual review of immunology, Vol. 21, pp. 231-64, (2003) (PubMed).

    Khare, Sarosi, Xia, McCabe, Miner, Solovyev, Hawkins, Kelley, Chang, Van, Ross, Delaney, Wang, Lacey, Boyle, Hsu: "Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 7, pp. 3370-5, (2000) (PubMed).

    Moore, Belvedere, Orr, Pieri, LaFleur, Feng, Soppet, Charters, Gentz, Parmelee, Li, Galperina, Giri, Roschke, Nardelli, Carrell, Sosnovtseva, Greenfield, Ruben, Olsen, Fikes, Hilbert: "BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator." in: Science (New York, N.Y.), Vol. 285, Issue 5425, pp. 260-3, (1999) (PubMed).

  • 抗原
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    别名
    Blys BAFF (TNFSF13B 产品)
    别名
    BAFF antibody, BLYS antibody, CD257 antibody, DTL antibody, TALL-1 antibody, TALL1 antibody, THANK antibody, TNFSF20 antibody, ZTNF4 antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, TNFSF13B antibody, RGD1561519 antibody, RGD1560810 antibody, BLyS antibody, D8Ertd387e antibody, zTNF4 antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, zgc:172115 antibody, TNF superfamily member 13b antibody, TNF receptor superfamily member 13C antibody, tumor necrosis factor (ligand) superfamily, member 13b antibody, tumor necrosis factor receptor superfamily, member 13c antibody, tumor necrosis factor superfamily member 13b antibody, TNFSF13B antibody, TNFRSF13C antibody, Tnfsf13b antibody, Tnfrsf13c antibody, tnfsf13b antibody
    途径
    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
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