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Lamin A/C 抗体 (AA 430-545)

Cited in 3+ publications. The 小鼠 单克隆 anti-Lamin A/C antibody (Clone 3A6-4C11) (ABIN2668844) specifically detects Lamin A/C in WB, IF 和 ICC. The antibody is reactive with 人, 小鼠, 大鼠, 猴 和 Hamster samples.
产品编号 ABIN2668844
发货至: 中国
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Quick Overview for Lamin A/C 抗体 (AA 430-545) (ABIN2668844)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

  • 174
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人, 小鼠, 大鼠, 猴, Hamster

宿主

  • 145
  • 42
  • 2
  • 1
小鼠

克隆类型

  • 106
  • 84
单克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

  • 160
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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

3A6-4C11
  • 抗原表位

    • 11
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    • 5
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    AA 430-545

    纯化方法

    Culture Supernatant

    免疫原

    This Lamin A/C antibody was raised against a recombinant protein corresponding to amino acids 430-545 of human Lamin A.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Cell culture supernatant containing mouse IgG, 30 % glycerol, 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    储存条件

    -20 °C

    储存方法

    Antibodies in solution can be stored at -20 °C for 2 years.

    有效期

    6 months
  • Gesson, Rescheneder, Skoruppa, von Haeseler, Dechat, Foisner: "A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha." in: Genome research, Vol. 26, Issue 4, pp. 462-73, (2016) (PubMed).

    Kim, Zheng: "Generation and characterization of a conditional deletion allele for Lmna in mice." in: Biochemical and biophysical research communications, Vol. 440, Issue 1, pp. 8-13, (2013) (PubMed).

    Eckersley-Maslin, Bergmann, Lazar, Spector: "Lamin A/C is expressed in pluripotent mouse embryonic stem cells." in: Nucleus (Austin, Tex.), Vol. 4, Issue 1, pp. 53-60, (2013) (PubMed).

  • 抗原

    Lamin A/C (LMNA)

    别名

    Lamin A/C

    分子量

    75 kDa

    基因ID

    4000

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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