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Retinoblastoma Binding Protein 8 抗体 (AA 620-897)

This 小鼠 单克隆 antibody specifically detects Retinoblastoma Binding Protein 8 in WB, IP, ICC 和 IF. It exhibits reactivity toward 人. It has been mentioned in 6+ publications
产品编号 ABIN2668263
发货至: 中国
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Quick Overview for Retinoblastoma Binding Protein 8 抗体 (AA 620-897) (ABIN2668263)

抗原

See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体
Retinoblastoma Binding Protein 8 (RBBP8)

适用

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宿主

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小鼠

克隆类型

  • 53
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单克隆

标记

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This Retinoblastoma Binding Protein 8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

14-1
  • 抗原表位

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    AA 620-897

    纯化方法

    Protein A Chromatography

    免疫原

    This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    储存条件

    -20 °C

    储存方法

    Antibodies in solution can be stored at -20 °C for 2 years.

    有效期

    6 months
  • Onyango, Howard, Neherin, Yanez, Stark: "Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." in: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).

    Bakr, Köcher, Volquardsen, Petersen, Borgmann, Dikomey, Rothkamm, Mansour: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." in: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).

    Zhou, Caron, Legube, Paull: "Quantitation of DNA double-strand break resection intermediates in human cells." in: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).

    Makharashvili, Tubbs, Yang, Wang, Barton, Zhou, Deshpande, Lee, Lobrich, Sleckman, Wu, Paull: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." in: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).

    Zhang, Jasin: "An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway." in: Nature structural & molecular biology, Vol. 18, Issue 1, pp. 80-4, (2011) (PubMed).

    Yu, Fu, Lai, Baer, Chen: "BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP." in: Genes & development, Vol. 20, Issue 13, pp. 1721-6, (2006) (PubMed).

  • 抗原

    Retinoblastoma Binding Protein 8 (RBBP8)

    别名

    CtIP

    分子量

    120 kDa

    基因ID

    5932

    途径

    Cell Division Cycle, DNA Damage Repair
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