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c-Rel 抗体

c-Rel 适用: 人 FACS 宿主: 小鼠 Monoclonal 2F5A22 unconjugated
产品编号 ABIN2666277
发货至: 中国
  • 抗原 See all c-Rel 抗体
    c-Rel (REL proto-oncogene (c-Rel))
    适用
    • 80
    • 22
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 74
    • 9
    • 1
    小鼠
    克隆类型
    • 67
    • 17
    单克隆
    标记
    • 38
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This c-Rel antibody is un-conjugated
    应用范围
    • 57
    • 32
    • 13
    • 13
    • 10
    • 10
    • 5
    • 4
    • 3
    • 3
    • 1
    Flow Cytometry (FACS)
    纯化方法
    Affinity purified
    克隆位点
    2F5A22
    亚型
    IgG2b kappa
    Top Product
    Discover our top product c-Rel Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Upon receipt, store undiluted between 2°C and 8°C.
  • 抗原
    c-Rel (REL proto-oncogene (c-Rel))
    别名
    C-REL (c-Rel 产品)
    背景
    C-Rel is a member of the Rel/NF-κB transcription factor family that forms homo or heterodimers with family members such as RelA/p65, RelB, NF- κB1/p105, and NF-κB2/p100. The NF-κB complex is retained in cytoplasm by the inhibitor IκB protein in unstimulated cells. Upon activation, IκB is degraded via the ubiquitin-proteasome pathway, which results in nuclear translocation of the active NF-κB complex. While other NF-κB transcription factors are expressed in most cell types, relatively higher levels of c-REL expression are found in hematopoietic cells. c-REL is thought to play key roles in regulating proliferation, differentiation, and survival of B and T lymphocytes.
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