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c-Rel 抗体

This anti-c-Rel antibody is a 小鼠 单克隆 antibody detecting c-Rel in FACS. Suitable for 人.
产品编号 ABIN2666277
发货至: 中国

Quick Overview for c-Rel 抗体 (ABIN2666277)

抗原

See all c-Rel 抗体
c-Rel (REL proto-oncogene (c-Rel))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This c-Rel antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

2F5A22
  • 纯化方法

    Affinity purified

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Upon receipt, store undiluted between 2°C and 8°C.
  • 抗原

    c-Rel (REL proto-oncogene (c-Rel))

    别名

    C-REL

    背景

    C-Rel is a member of the Rel/NF-κB transcription factor family that forms homo or heterodimers with family members such as RelA/p65, RelB, NF- κB1/p105, and NF-κB2/p100. The NF-κB complex is retained in cytoplasm by the inhibitor IκB protein in unstimulated cells. Upon activation, IκB is degraded via the ubiquitin-proteasome pathway, which results in nuclear translocation of the active NF-κB complex. While other NF-κB transcription factors are expressed in most cell types, relatively higher levels of c-REL expression are found in hematopoietic cells. c-REL is thought to play key roles in regulating proliferation, differentiation, and survival of B and T lymphocytes.
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