c-Rel 抗体
Our Local Distributor
北京 101111
Quick Overview for c-Rel 抗体 (ABIN2666277)
抗原
See all c-Rel 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Affinity purified
-
亚型
- IgG2b kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Upon receipt, store undiluted between 2°C and 8°C.
-
-
- c-Rel (REL proto-oncogene (c-Rel))
-
别名
- C-REL
-
背景
- C-Rel is a member of the Rel/NF-κB transcription factor family that forms homo or heterodimers with family members such as RelA/p65, RelB, NF- κB1/p105, and NF-κB2/p100. The NF-κB complex is retained in cytoplasm by the inhibitor IκB protein in unstimulated cells. Upon activation, IκB is degraded via the ubiquitin-proteasome pathway, which results in nuclear translocation of the active NF-κB complex. While other NF-κB transcription factors are expressed in most cell types, relatively higher levels of c-REL expression are found in hematopoietic cells. c-REL is thought to play key roles in regulating proliferation, differentiation, and survival of B and T lymphocytes.
抗原
-