TCP1 alpha/CCTA 抗体
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- 抗原 See all TCP1 alpha/CCTA (TCP1) 抗体
- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TCP1 alpha/CCTA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应 (详细)
- Recognizes ΔN-isoforms
- 纯化方法
- The antibody was purified by antigen-affinity chromatography.
- 克隆位点
- Poly6190
- 亚型
- IgG
- Top Product
- Discover our top product TCP1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Upon receipt, store frozen at -20°C.
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- 抗原
- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
- 别名
- p63 (TCP1 产品)
- 别名
- CCT-alpha antibody, CCT1 antibody, CCTa antibody, D6S230E antibody, TCP-1-alpha antibody, AI528772 antibody, CCT antibody, Cct1 antibody, Ccta antibody, TRic antibody, Tcp-1 antibody, Tp63 antibody, c-cpn antibody, p63 antibody, TRiC antibody, CCTalpha antibody, BEST:GH05123 antibody, CG5374 antibody, Dmel\\CG5374 antibody, T-cpl antibody, TCP-1alpha antibody, TCPA_DROME antibody, Tcp1 antibody, Tcp1-alpha antibody, gh05123 antibody, cct-alpha antibody, ccta antibody, tcp1 antibody, tcp1-a antibody, tcp1a antibody, tcp1alpha antibody, CHUNP6875 antibody, fa13h08 antibody, wu:fa13h08 antibody, wu:fc95g06 antibody, t-complex 1 antibody, T-complex protein 1 subunit alpha antibody, t-complex protein 1 antibody, Tcp1-like antibody, t-complex 1 S homeolog antibody, TCP1 antibody, cct-1 antibody, Tcp1 antibody, T-cp1 antibody, tcp1.S antibody, tcp1 antibody
- 背景
- P63 (ΔN) is a member of the p53 family. This protein has multiple isoforms TA p63-α, -β, γ, ΔN p63-α, -β, and -γ. The molecular weights of the p63 isoforms α=66 kD, β=52 kD, and γ=45 kD. This nuclear protein is essential for limb formation, epidermal morphogenesis, and epithelial stem cell regeneration. δN isoforms are antagonistic to p53, TA isoforms can transactivate p53 targets. The p63 ΔN isoforms repress TA isoforms, mutant p53 abrogates p63 transactivation. This protein interacts with p53, p73, and the various TA- and ΔN isoforms. The Poly6190 antibody recognizes human p63 ΔN isoforms and has been shown to be useful for Western blotting.
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