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Caspase 8 抗体

This anti-Caspase 8 antibody is a 大鼠 单克隆 antibody detecting Caspase 8 in FACS. Suitable for 人.
产品编号 ABIN2666061
发货至: 中国

Quick Overview for Caspase 8 抗体 (ABIN2666061)

抗原

See all Caspase 8 (CASP8) 抗体
Caspase 8 (CASP8)

适用

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宿主

  • 134
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大鼠

克隆类型

  • 131
  • 36
单克隆

标记

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  • 1
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This Caspase 8 antibody is un-conjugated

应用范围

  • 150
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Flow Cytometry (FACS)

克隆位点

1H10
  • 纯化方法

    The antibody was purified by affinity chromatography

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Upon receipt, store between 2°C and 8°C.
  • 抗原

    Caspase 8 (CASP8)

    别名

    Caspase-8

    背景

    Caspase-8 is involved in the apoptosis mediated by CD95 and TNFR-1. It is suggested that following the triggering of apoptosis by CD95 or TNFR-1, the adaptor molecule FADD interact physically with cytosolic caspase-8 and initiate the apoptotic cascade. The active caspase-8 consists of two subunits of p18 and p10. This antibody should recognize the whole length of human caspase-8 and some isofrms of lower MW.

    途径

    Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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