×
我们推荐在您的浏览器上开启Javascript,以获得最佳效果。
P2RX7 抗体
P2RX7
适用: 小鼠
FACS
宿主: 大鼠
Monoclonal
1F11
unconjugated
P2RX7抗体详情
(hide)
抗原
See all P2RX7 抗体
P2RX7
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
适用
All reactivities for P2RX7 抗体
小鼠
宿主
All hosts for P2RX7 抗体
大鼠
克隆类型
All clonalities for P2RX7 抗体
单克隆
标记
All conjugates for P2RX7 抗体
This P2RX7 antibody is un-conjugated
应用范围
All applications for P2RX7 抗体
Flow Cytometry (FACS)
纯化方法
The antibody was purified by affinity chromatography.
克隆位点
1F11
亚型
IgG2b kappa
Top Product
Discover our top product P2RX7 Primary Antibody
Alternatives
(show)
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibody
P2RX7
适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠
WB, IHC
宿主: 兔
Polyclonal
unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 136-152), (Extracellular Loop) antibody
P2RX7
适用: 人, 小鼠, 大鼠
WB, IHC, FACS, IF, ICC, LCI
宿主: 兔
Polyclonal
unconjugated
使用细节
(hide)
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
(hide)
浓度
0.5 mg/mL
缓冲液
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
The antibody solution should be stored undiluted between 2°C and 8°C.
P2RX7目标详情
(hide)
抗原
P2RX7
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
别名
P2X7R (P2RX7 产品 )
别名
p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
背景
P2X7R, also known as P2X7 receptor, belongs to the family of ligand-gated ion channel receptors. It is expressed on T cells, B cells, macrophages, and microglia. The receptor opens in the presence of extracellular ATP or NAD, leading to intracellular calcium mobilization. P2X7R activation requires higher concentrations of ATP compared to other P2X receptors. Longer stimulation results in larger pores, allowing passage of larger molecules. Activation of these molecules also leads to mitochondrial and cytoskeletal changes as well as IL-1β maturation and release. Ligation of P2X7 receptor can lead to membrane blebbing and cell death.
途径
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Synaptic Vesicle Exocytosis
Recently viewed
(hide)