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- 抗原 See all IL-6 (IL6) 抗体
- IL-6 (IL6) (Interleukin 6 (IL6))
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适用
- 大鼠
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This IL-6 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- Poly5177
- Top Product
- Discover our top product IL6 Primary Antibody
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anti-Interleukin 6 (IL6) (AA 111-150) antibody
IL6 适用: 人, 小鼠, 大鼠, 兔, Cow WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 (IL6) antibodyIL6 适用: 人 ELISA, FACS, Func, ELISpot 宿主: 小鼠 Monoclonal B-E8 unconjugated
anti-Interleukin 6 (IL6) (AA 21-211) antibodyIL6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Interleukin 6 (IL6) (AA 27-212) antibodyIL6 适用: 猕猴 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 18# unconjugated
anti-Interleukin 6 (IL6) (AA 21-211) antibodyIL6 适用: 大鼠 WB, IHC, IP, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Interleukin 6 (IL6) (AA 101-150) antibodyIL6 适用: 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 (IL6) (AA 27-241) antibodyIL6 适用: 兔 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C305 unconjugated
anti-Interleukin 6 (IL6) (AA 25-211) antibodyIL6 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 (IL6) (AA 27-55) antibodyIL6 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 (IL6) (AA 26-50) antibodyIL6 适用: 人, 大鼠 ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- IL-6 (IL6) (Interleukin 6 (IL6))
- 别名
- IL-6 (IL6 产品)
- 背景
- Interleukin 6 (IL-6) is a prototypic member of the IL-6 superfamily of cytokines. IL-6 is secreted by a variety of lymphoid and non-lymphoid cells including T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells, keratinocytes, etc. Mature Rat IL-6 is a 187 aa residue protein. At the protein sequence level, there is approximately 39 % identity between rat and human IL-6, and 87 % identity between mouse and rat IL-6. The production of IL-6 can be induced by numerous signals such as mitogenic or antigenic stimulation, lipopolysaccharides, calcium ionophores, cytokines, and viruses. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R) and a subunit (gp130) that acts as the universal signal-transducing element for all IL-6 family cytokines. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. One of the most important mechanism is that IL-6 is a key factor that reciprocally regulates Th17 and Foxp3+ Treg differentiation by inhibition of TGF-β induced Foxp3 and induction of RORγt, a Th17 lineage-specific transcription factor. Elevated serum IL-6 levels have been observed in a number of pathological conditions, including bacterial and viral infections, trauma, autoimmune diseases, inflammations and malignancies.
- 途径
- TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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