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DDX1 抗体

DDX1 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal 9F12B04 unconjugated
产品编号 ABIN2664923
发货至: 中国
  • 抗原 See all DDX1 抗体
    DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))
    适用
    • 28
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    • 5
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    • 3
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    • 2
    • 1
    人, 小鼠
    宿主
    • 23
    • 5
    小鼠
    克隆类型
    • 24
    • 4
    单克隆
    标记
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This DDX1 antibody is un-conjugated
    应用范围
    • 19
    • 8
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    • 4
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    9F12B04
    亚型
    IgG1 kappa
    Top Product
    Discover our top product DDX1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))
    别名
    DDX1 (DDX1 产品)
    别名
    CG9054 antibody, DDX1 antibody, Dbp79E antibody, DmDDX1 antibody, DmRH12 antibody, Dmel\\CG9054 antibody, anon-79E antibody, DBP-RB antibody, UKVH5d antibody, si:ch211-214k9.2 antibody, si:dkey-161f12.1 antibody, AA409185 antibody, Dead-box-1 antibody, DEAD-box helicase 1 antibody, DEAD/H-box helicase 1 L homeolog antibody, DEAD (Asp-Glu-Ala-Asp) box helicase 1 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 antibody, Ddx1 antibody, DDX1 antibody, ddx1.L antibody, ddx1 antibody
    背景
    DDX1, also known as DEAD box protein retinoblastoma, is a member of the DEAD (Asp-Glu-Ala-Asp)-box RNA helicase family. DDX1 possesses RNA nuclease, binding, unwinding, and ATPase activities, and is thus involved in RNA metabolism, pre-mRNA splicing, translation initiation, and ribosome biogenesis. DDX1 interacts with the Rev protein of HIV-1 and has been shown to be crucial in the viral RNA replication. DDX1 was found to locate to the area of DNA damage induced by ionizing radiation and is implicated to participate in double-strand DNA break repair. DDX1 also acts as a transcriptional coactivator to facilitate NF-κB mediated gene activation. Elevated expression of DDX1 was observed in a number of tumors such as retinoblastoma, neuroblastoma, and testicular carcinoma. The accumulation of DDX1 is associated with cancer metastasis and poor survival.
    途径
    Ribonucleoprotein Complex Subunit Organization
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